Gul Daglar, M. D. , Turgut Karaca, M. D. , Yunus Nadi Yuksek, M. D

Slides:

Advertisements

Similar presentations

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

Advertisements

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr

2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.

Other options in the treatment of fecal incontinence Paul A. Lehur, MD, PhD, Emilie Duchalais, MD Seminars in Colon and Rectal Surgery Volume 27, Issue.

Preoperative Evaluations: The Very Last Chance To Identify a Problem With a Pacemaker or Implanted Cardioverter-Defibrillator Marc A. Rozner, PhD, MD Journal.

How surgeons can find information online? Martin Hewitt International Journal of Surgery Volume 5, Issue 6, Pages (December 2007) DOI: /j.ijsu

Effect of inhaled tacrolimus on ischemia reperfusion injury in rat lung transplant model Johanna Bayer, MD, Nitin A. Das, MD, Clinton E. Baisden, MD, Meenakshi.

The protective effect of curcumin on ischemia-reperfusion injury in rat ovary Muhammet Erdal Sak, Hatice Ender Soydinc, Sibel Sak, Mehmet Siddik Evsen,

Open access phone triage for veterans with suspected malignant pleural mesothelioma Charles Jeff Siegert, MD, Piero Marco Fisichella, MD, MBA, FACS, Jennifer.

Tetrahydrocurcumin provides neuroprotection in rats after traumatic brain injury: autophagy and the PI3K/AKT pathways as a potential mechanism Yongyue.

Treating a collagen scaffold with a low concentration of nicotine promoted angiogenesis and wound healing Pham Hieu Liem, MD, MSc, Naoki Morimoto, MD,

Effects of Myrtus communis extract treatment in bile duct ligated rats

Applying fault tree analysis to the prevention of wrong-site surgery

Behzad Kasravi, M. D. , Ph. D. , Diana H. Lee, B. S. , Jean W. Lee, B

Laparoscopic surgery for orthotopic kidney transplant in the pig model

The effect of coenzyme Q10 on venous ischemia reperfusion injury

Volume 21, Issue 7, Pages (July 2005)

Eradication of Helicobacter pylori for prevention of ulcer recurrence after simple closure of perforated peptic ulcer: A meta-analysis of randomized controlled.

Local Insulin-Zinc Injection Accelerates Skin Donor Site Wound Healing

Cell Suspensions of Autologous Keratinocytes or Autologous Fibroblasts Accelerate the Healing of Full Thickness Skin Wounds in a Diabetic Porcine Wound.

Journal of Surgical Research

Novel anti-adhesive barrier Biobarrier reduces growth of colon cancer cells Monika Posaric-Bauden, MSc, Karolin Isaksson, MD, PhD, Daniel Åkerberg, MD,

Antioxidant and antigenotoxic effects of lycopene in obstructive jaundice Sevtap Aydın, PhD, Mehmet Tokaç, MD, PhD, Gökçe Taner, MSc, Ata Türker Arıkök,

Limb ischemia–reperfusion differentially affects the periosteal and synovial microcirculation Petra Hartmann, MD, PhD, Gábor Erős, MD, PhD, Renáta Varga,

Effect of sex steroids on soleus muscle response in hypocalcemic medium (in vitro) S. Said Kökçam, MD, Şakir Tekin, MD, Adil Kartal, MD, Murat Ayaz, PhD,

Thymoquinone treatment against acetaminophen-induced hepatotoxicity in rats İlker Öngüç Aycan, Adnan Tüfek, Orhan Tokgöz, Osman Evliyaoğlu, Uğur Fırat,

Spontaneous Umbilical Cord Hematoma

The protective effect of curcumin on ischemia-reperfusion injury in rat ovary Muhammet Erdal Sak, Hatice Ender Soydinc, Sibel Sak, Mehmet Siddik Evsen,

AJKD Atlas of Renal Pathology: Ischemic Acute Tubular Injury

Volume 1, Issue 1, Pages (June 2007)

Venturing Out on a Limb: Axillary Web Syndrome

Expression of PD-L1 in mastocytosis

Was It the Zebu? The American Journal of Medicine

An Iatrogenic Metastasis

Pseudohyperplastic Adenocarcinoma of the Prostate

Iatrogenic hyperpigmentation in chronically infected hepatitis C patients treated with pegylated interferon and ribavirin Jennifer Lin, MD, Jason P.

Peter C. Schalock, MD, Jeoffrey B. Brennick, MD, James G. H

Freebie Rhabdomyolysis: A Public Health Concern

Thymoquinone treatment against acetaminophen-induced hepatotoxicity in rats İlker Öngüç Aycan, Adnan Tüfek, Orhan Tokgöz, Osman Evliyaoğlu, Uğur Fırat,

Quiz American Journal of Kidney Diseases

Stuttering Mesenteric Ischemia

Protective effects of montelukast on ischemia-reperfusion injury in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation

Treatment of hepatitis C

A Diagnostic Dilemma in a Patient with Polyarthritis

Annie Wester, MD, MS, Jennifer T. Eyler, MD, James W. Swan, MD

Infliximab in the treatment of a child with cutaneous granulomas associated with ataxia telangiectasia Angana Mitra, MBChB, Jimmy Gooi, MBChB, Jonathan.

Cytomegalovirus esophagitis in an immunocompetent host

Quiz Page December 2008 American Journal of Kidney Diseases

Occult active giant cell aortitis necessitating surgical repair

Sidhu P. Gangadharan, BS, Robert J. Wagner, BS, Jack L. Cronenwett, MD

Copyright © 2013 Elsevier Inc. All rights reserved.

Unusual Cause of Stridor in an 80-Year-old Man

Acute Pyelonephritis American Journal of Kidney Diseases

A 63-Year-Old Man With Hepatitis C and Nephrotic Syndrome

Not What She Had in Mind The American Journal of Medicine

Treatment of Colorectal Cancer

Manfred Bilzer, Gustav Paumgartner, Alexander L. Gerbes

Volume 62, Issue 3, Pages (March 2015)

A Post-cure Complication

Glucagon potentiates intestinal reperfusion injury

Quiz Page June 2009 American Journal of Kidney Diseases

Direct Observation of Residents: A Model for an Assessment System

A sphingosine-1-phosphate type 1 receptor agonist inhibits the early T-cell transient following renal ischemia–reperfusion injury L.-W. Lai, K.-C. Yong,

Quiz Page January 2010 American Journal of Kidney Diseases

Toll-like receptor 4 inhibition attenuates ischemia-reperfusion injury in rats: Will it work in human beings? Chadrick E. Denlinger, MD The Journal.

Michael Conroy, MD, MS, Lindsay Sewell, MD, O

Toward a More Responsible News Media

AJKD Atlas of Renal Pathology: Ischemic Acute Tubular Injury

A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia- reperfusion in mice Alik Farber, MD, John P. Connors, MD, Robert.

Presentation transcript:

Effect of Montelukast and MK-886 on Hepatic Ischemia-Reperfusion Injury in Rats Gul Daglar, M.D., Turgut Karaca, M.D., Yunus Nadi Yuksek, M.D., Ugur Gozalan, M.D., Filiz Akbiyik, M.D., Ph.D., Cenk Sokmensuer, M.D., Bora Gurel, M.D., Nuri Aydin Kama, M.D. Journal of Surgical Research Volume 153, Issue 1, Pages 31-38 (May 2009) DOI: 10.1016/j.jss.2008.02.052 Copyright © 2009 Elsevier Inc. Terms and Conditions

FIG. 1 Histology of the liver in the control and treatment groups. (A) The I/R group showed extensive panacinar congestion. (B) In control+LT inhibition groups, minimal damage mostly in zone 3 and megamitochondri were seen. (C) In I/R+LT inhibition groups, only zone 2 and/or 3 involvement with megamitochondri and microvesicular fatty change were observed (A, HE staining; original magnification, 100×; B and C, HE staining; original magnification, 200×). (Color version of figure is available online.) Journal of Surgical Research 2009 153, 31-38DOI: (10.1016/j.jss.2008.02.052) Copyright © 2009 Elsevier Inc. Terms and Conditions

FIG. 2 Histology of the small intestine in the control and treatment groups. (A) The I/R group showed 2/3 of villus loss, apoptotic fragmentation, congestion and lymphatic dilation, villi denudation. (B) In control+LT inhibition groups, limited lymphatic dilation and preservation of villi structures were seen. (C) In I/R+LT inhibition groups, 1/3 loss of villi and superficial epithelial sloughing were seen (HE staining; original magnification, 200×). (Color version of figure is available online.) Journal of Surgical Research 2009 153, 31-38DOI: (10.1016/j.jss.2008.02.052) Copyright © 2009 Elsevier Inc. Terms and Conditions

FIG. 3 Hepatic and intestinal mean apoptotic cells in groups. Journal of Surgical Research 2009 153, 31-38DOI: (10.1016/j.jss.2008.02.052) Copyright © 2009 Elsevier Inc. Terms and Conditions

FIG. 4 Hepatic and intestinal MDA levels in groups. Journal of Surgical Research 2009 153, 31-38DOI: (10.1016/j.jss.2008.02.052) Copyright © 2009 Elsevier Inc. Terms and Conditions

FIG. 5 Hepatic and intestinal GSH levels in groups. Journal of Surgical Research 2009 153, 31-38DOI: (10.1016/j.jss.2008.02.052) Copyright © 2009 Elsevier Inc. Terms and Conditions