3T MRI in paediatrics: Challenges and clinical applications

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Presentation transcript:

3T MRI in paediatrics: Challenges and clinical applications Charuta Dagia, Michael Ditchfield  European Journal of Radiology  Volume 68, Issue 2, Pages 309-319 (November 2008) DOI: 10.1016/j.ejrad.2008.05.019 Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Axial T2 images from serial 3T MRI brain studies of a premature infant (34 weeks gestation) obtained 7 days (a) and 6 weeks (b) after birth demonstrate temporal maturation of the sulcal pattern, and progressive myelination in the posterior limbs of internal capsules and ventro-lateral thalami. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Histologically confirmed cortical dysplasia: coronal T2 FLAIR images from MRI brain study performed at 3T (a) demonstrates ill-defined increased signal in the right insular cortex and adjacent white matter, much better appreciated than on (b) the earlier study performed at 1.5T, (c) axial T2 image of a term neonate with polymicrogyria, (d) axial T2 true FISP MRI of the cervical spine in a 3-month-infant demonstrates avulsed right C6 ventral nerve root and traumatic pseudo-meningocoele due to obstetric brachial plexus palsy, (e) MRCP of a patient with a choledochocele and (f) sagittal T2 FSE images demonstrate recto-sigmoid wall oedema and thickening due to inflammatory bowel disease. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Axial T2 FSE MRI brain images obtained at 3T: the claustrum (a) is well demonstrated in this term neonate, (b) the perivascular spaces are routinely visualised at 3T. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 Axial T1 image from MRI brain study of a neonate. The image contrast is less due to the prolonged T1 time, and the high water content of non-myelinated white matter. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 5 Moya Moya disease. Maximum intensity projection of time-of-flight MR brain angiogram demonstrates marked irregularity, narrowing of several vessels of the circle of Willis, with collateral neovascularisation. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 6 (a) Foci of profound signal loss due to haemosiderin on the susceptibility weighted image on follow-up MRI brain study after trauma (b) these are only identified in retrospect on the axial T2 images. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 7 3T proton MRS (TE 30 PRESS) from the parietal white matter of a child with guanidinoacetate methyltransferase (GAMT) deficiency demonstrating a dramatic reduction in the creatine peak. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 8 Glioblastoma Multiforme: Axial images from MRI brain study performed for right homonymous hemianopia demonstrate (a) gyral thickening, ill-defined increased T2 signal and indistinct grey-white differentiation in the left parieto-occipital region. (b) Cortically based enhancement (c) MR spectroscopy demonstrates marked elevation of choline away from the small central enhancing area – this is useful to delineate tumour extent, and distinguish infiltrative spread from peri lesional oedema. (d) foci of signal dropout from blood degradation products. Note the skull base susceptibility artefact. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 9 Restricted diffusion on (a) DWI and (b) the ADC Map in the ganglio thalamic regions in a term infant with severe hypoxic ischaemic encephalopathy – it may present with subtle findings on the routine sequences (a) faint increased T1 signal in the ganglio thalamic regions bilaterally, (b) low T2 signal on the left, also in the hippocampus, are confidently identified on correlation. (e) MRS revealed marked, global lactate elevation. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 10 Coronal T2 STIR whole body MRI for metastatic neuroblastoma. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 11 Sequela of right middle cerebral artery embolic occlusion secondary to traumatic internal carotid artery dissection. (a) Axial T2 image demonstrates cystic encephalomalacia and volume loss (b) disruption of the major white matter tracts (colour coded) as depicted by tractography. European Journal of Radiology 2008 68, 309-319DOI: (10.1016/j.ejrad.2008.05.019) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions