Copyright © 2009 American Medical Association. All rights reserved. From: Perioperative Supplemental Oxygen Therapy and Surgical Site InfectionA Meta-analysis of Randomized Controlled Trials Arch Surg. 2009;144(4):359-366. doi:10.1001/archsurg.2009.1 Figure Legend: Literature search results (Quality of Reports of Meta-analyses [QUOROM] flowchart). ARDS indicates adult respiratory distress syndrome. Date of download: 10/13/2017 Copyright © 2009 American Medical Association. All rights reserved.

Copyright © 2009 American Medical Association. All rights reserved. From: Perioperative Supplemental Oxygen Therapy and Surgical Site InfectionA Meta-analysis of Randomized Controlled Trials Arch Surg. 2009;144(4):359-366. doi:10.1001/archsurg.2009.1 Figure Legend: Effect of perioperative supplemental oxygen therapy on surgical site infection risk reduction. Risk ratios (RRs) with 95% confidence intervals (CIs) are shown for individual, combined, and sensitivity analysis (SA) values. 1 indicates Mayzler et al (RR, 0.667; 95% CI, 0.125-3.550; P = .64); 2, Pryor et al (2.222; 1.078-4.580; P = .03); 3, Belda et al (0.607; 0.375-0.983; P = .04); 4, Greif et al (0.464; 0.246-0.875; P = .02); 5, Myles et al (0.740; 0.559-0.979; P = .04); overall (0.742; 0.599-0.919; P = .006; I2 = 65.584); SA1, noncolorectal studies excluded (0.556; 0.383-0.808; P = .002; I2 = 0.000); SA2, nitrous oxide studies excluded (0.551; 0.375-0.808; P = .002; I2 = 0.000); SA3, the study by Pryor et al excluded (0.667; 0.533-0.835; P = .000; I2 = 0.000); and SA4, the largest study excluded (0.744; 0.534-1.037; P = .08; I2 = 74.186). Squares represent individual randomized controlled trials; lines attached to squares, individual 95% confidence intervals; diamonds, the combined effect of several (or all) meta-analyses. Date of download: 10/13/2017 Copyright © 2009 American Medical Association. All rights reserved.

Copyright © 2009 American Medical Association. All rights reserved. From: Perioperative Supplemental Oxygen Therapy and Surgical Site InfectionA Meta-analysis of Randomized Controlled Trials Arch Surg. 2009;144(4):359-366. doi:10.1001/archsurg.2009.1 Figure Legend: Funnel plot to visually detect publication bias. Circles correspond to individual studies; diamond, logarithm of the overall risk ratio; and 0, no effect and equivalent to a risk ratio of 1. Date of download: 10/13/2017 Copyright © 2009 American Medical Association. All rights reserved.