Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: The Genes-environments and Admixture in Latino Asthmatics.

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Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: The Genes-environments and Admixture in Latino Asthmatics (GALA II) study Rajesh Kumar, MD, MS, Elizabeth A. Nguyen, BS, Lindsey A. Roth, MA, Sam S. Oh, PhD, MPH, Christopher R. Gignoux, MS, Scott Huntsman, MS, Celeste Eng, BA, Andres Moreno-Estrada, MD, PhD, Karla Sandoval, PhD, Rosenda I. Peñaloza-Espinosa, PhD, Marisol López-López, PhD, Pedro C. Avila, MD, Harold J. Farber, MD, MSPH, Haig Tcheurekdjian, MD, William Rodriguez-Cintron, MD, Jose R. Rodriguez-Santana, MD, Denise Serebrisky, MD, Shannon M. Thyne, MD, L. Keoki Williams, MD, MPH, Cheryl Winkler, PhD, Carlos D. Bustamante, PhD, Eliseo J. Pérez-Stable, MD, Luisa N. Borrell, DDS, PhD, Esteban G. Burchard, MD, MPH Journal of Allergy and Clinical Immunology Volume 132, Issue 4, Pages 896-905.e1 (October 2013) DOI: 10.1016/j.jaci.2013.02.046 Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Proportion of participants with a positive skin test response to allergens tested by region of origin. The proportions are represented on a scale in increments of 0.1, ranging from 0 (white) to 1.0 (black). Journal of Allergy and Clinical Immunology 2013 132, 896-905.e1DOI: (10.1016/j.jaci.2013.02.046) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Global ancestry proportions of GALA II Latinos by origin and recruitment site. Diameter of pie charts represents the size of group recruited at each site. Blue, yellow, and orange wedges represent African, European, and Native American ancestry, respectively. Global ancestry proportions for population sizes of less than 20 are not displayed on this map. Journal of Allergy and Clinical Immunology 2013 132, 896-905.e1DOI: (10.1016/j.jaci.2013.02.046) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Ancestral proportions and recruitment site and case-control status. Each plot on these graphs represents a recruitment site. The y-axis represents global estimates of individual Native American ancestral proportion, and the x-axis represents global estimates of individual African ancestral proportion. Asthmatic patients are represented by squares, and nonasthmatic subjects are represented by circles. Journal of Allergy and Clinical Immunology 2013 132, 896-905.e1DOI: (10.1016/j.jaci.2013.02.046) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions