Sequential events in fertilization in mammals

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Sequential events in fertilization in mammals Sequential events in fertilization in mammals. Sperm are attracted to the ovum, bind to the zona pellucida, release acrosomal enzymes, penetrate the zona pellucida, and fuse with the membrane of the ovum, releasing the sperm nucleus into its cytoplasm. Current evidence indicates that the side, rather than the tip, of the sperm head fuses with the egg cell membrane. (Modified with permission from Vacquier VD: Evolution of gamete recognition proteins. Science 1998; Sep 25; 281(5385):1995–1998.) Source: Reproductive Development & Function of the Female Reproductive System, Ganong’s Review of Medical Physiology, 25e Citation: Barrett KE, Barman SM, Boitano S, Brooks HL. Ganong’s Review of Medical Physiology, 25e; 2016 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/1587/bar_ch22_f020.png&sec=97164678&BookID=1587&ChapterSecID=97164484&imagename= Accessed: October 13, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved