The Use of Hormone Therapy Alone Versus Hormone Therapy and Radiation Therapy for Breast Cancer in Elderly Women: A Population-Based Study Alan M. Nichol,

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The Use of Hormone Therapy Alone Versus Hormone Therapy and Radiation Therapy for Breast Cancer in Elderly Women: A Population-Based Study Alan M. Nichol, MD, Elisa K. Chan, MD, Sarah Lucas, MD, Sally L. Smith, MD, Lovedeep Gondara, PDC, Caroline Speers, BA, Scott Tyldesley, MD, MSc International Journal of Radiation Oncology • Biology • Physics Volume 98, Issue 4, Pages 829-839 (July 2017) DOI: 10.1016/j.ijrobp.2017.02.094 Copyright © 2017 Elsevier Inc. Terms and Conditions

Fig. 1 Survival outcomes by treatment group: locoregional relapse–free survival (A) and breast cancer–specific survival (B). Abbreviations: ET = hormone therapy; ET + RT = hormone therapy and radiation therapy. International Journal of Radiation Oncology • Biology • Physics 2017 98, 829-839DOI: (10.1016/j.ijrobp.2017.02.094) Copyright © 2017 Elsevier Inc. Terms and Conditions

Fig. 2 Significant predictors of overall survival: Charlson comorbidity score of 0 versus 1 versus ≥2 (A) and age of 70 to 74 years versus 75 to 79 years (B). International Journal of Radiation Oncology • Biology • Physics 2017 98, 829-839DOI: (10.1016/j.ijrobp.2017.02.094) Copyright © 2017 Elsevier Inc. Terms and Conditions

Fig. 3 Significant predictors of event-free survival: histologic grade (A), lymphovascular invasion (LVI) (B), and treatment group (C). Abbreviations: ET = hormone therapy; ET + RT = hormone therapy and radiation therapy. International Journal of Radiation Oncology • Biology • Physics 2017 98, 829-839DOI: (10.1016/j.ijrobp.2017.02.094) Copyright © 2017 Elsevier Inc. Terms and Conditions

Fig. 4 Hormone therapy adherence by treatment group (A) and survival outcomes by adherence: locoregional relapse–free survival (B) and breast cancer–specific survival (C). Abbreviations: ET = hormone therapy; ET + RT = hormone therapy and radiation therapy. International Journal of Radiation Oncology • Biology • Physics 2017 98, 829-839DOI: (10.1016/j.ijrobp.2017.02.094) Copyright © 2017 Elsevier Inc. Terms and Conditions