Small cell neuroendocrine carcinoma of the esophagus

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Small cell neuroendocrine carcinoma of the esophagus Yu-Ling Huang  The Kaohsiung Journal of Medical Sciences  Volume 31, Issue 2, Pages 108-109 (February 2015) DOI: 10.1016/j.kjms.2014.11.007 Copyright © 2014 Terms and Conditions

Figure 1 A 48-year-old female. (A) Endoscopy reveals an elevated submucosal mass covered with normal mucosa in the esophagus. (B) Positron emission tomography/computed tomography revealed fluorodeoxyglucose accumulation in the lesion of the middle esophagus. Resected surgical specimen. (C) The tumor cells have scant cytoplasm, hyperchromatic nuclei, and absent or inconspicuous nucleoli (hematoxylin–eosin stain, original magnification 400×). (D) The scattered tumor cells show positive staining for synaptophysin (original magnification, 400×). (E) More than 20% of the nuclei are positive for Ki-67 (original magnification, 400×). The Kaohsiung Journal of Medical Sciences 2015 31, 108-109DOI: (10.1016/j.kjms.2014.11.007) Copyright © 2014 Terms and Conditions