Predictive factors for outcomes after reduced intensity conditioning hematopoietic stem cell transplantation for hematological malignancies: a 10-year.

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Presentation transcript:

Predictive factors for outcomes after reduced intensity conditioning hematopoietic stem cell transplantation for hematological malignancies: a 10-year retrospective analysis from the Société Française de Greffe de Moelle et de Thérapie Cellulaire Mauricette Michallet, Quoc-Hung Le, Mohamad Mohty, Thomas Prébet, Franck Nicolini, Jean Michel Boiron, Hélène Esperou, Michel Attal, Noel Milpied, Bruno Lioure, Pierre Bordigoni, Ibrahim Yakoub-Agha, Jean-Henri Bourhis, Bernard Rio, Eric Deconinck, Marc Renaud, Zina Chir, Didier Blaise Experimental Hematology Volume 36, Issue 5, Pages 535-544 (May 2008) DOI: 10.1016/j.exphem.2008.01.017 Copyright © 2008 ISEH - Society for Hematology and Stem Cells Terms and Conditions

Figure 1 Probability of overall survival with Kaplan-Meier method according to presence or absence of chronic graft-vs-host disease (CGVHD) (all study population analyzed). X axis represents time after transplantation and the Y axis delineates survival probability. Experimental Hematology 2008 36, 535-544DOI: (10.1016/j.exphem.2008.01.017) Copyright © 2008 ISEH - Society for Hematology and Stem Cells Terms and Conditions

Figure 2 Probability of overall survival with Kaplan-Meier method according to conditioning regimen. (A) According to the category of conditioning. (B) According to category of conditioning and ATG dose. ATG = anti-thymocyte globulins; Bus = busulfan; Fluda = fludarabine. 1 d = 1 day, 2.5 mg/kg; 2d = 2 days, 5 mg/kg; 3d = 3 days, 7.5 mg/kg; 4d = 4 days, 10 mg/kg; 5d = 5 days, 12.5 mg/kg; TBI = total body irradiation. X-axis represents time after transplantation and the Y-axis delineates survival probability. Experimental Hematology 2008 36, 535-544DOI: (10.1016/j.exphem.2008.01.017) Copyright © 2008 ISEH - Society for Hematology and Stem Cells Terms and Conditions

Figure 3 Probability of overall survival with Kaplan-Meier method according to type of ABO compatibility. Patient and donor ABO compatible/patient and donor with minor or major ABO incompatibility. X-axis represents time after transplantation and the Y-axis delineates survival probability. Experimental Hematology 2008 36, 535-544DOI: (10.1016/j.exphem.2008.01.017) Copyright © 2008 ISEH - Society for Hematology and Stem Cells Terms and Conditions