Electrical activity of a single dorsal horn neuron that had input from the thoracolumbar fascia and other tissues. Recording site: spinal segment L2. A,

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Electrical activity of a single dorsal horn neuron that had input from the thoracolumbar fascia and other tissues. Recording site: spinal segment L2. A, Response to brushing of the skin of the thigh and pinching of the fascia at the level of vertebra L5. LB, low back. B, Response to the injection of hypertonic saline (5%, 50 µL) into the erector spinae muscle at the level of vertebrae L4 to L5. The neuron also responded to weak deformation and noxious pressure of the same muscle (not shown). C, Approximate location and size of the receptive fields (RFs) of the neuron. Note the marked input convergence of this neuron from many tissues (fascia, skin, muscle) and receptor types (low-threshold mechanoreceptors and nociceptors). The neuron was dominated by input from nociceptors and behaved like a nociceptive wide-dynamic range (WDR) neuron. It may mediate pain from the soft tissues of the low back. (Modified after Taguchi et al.106) Source: Muscle Pain: Pathophysiology, Evaluation, and Treatment, Principles and Practice of Pain Medicine, 3e Citation: Bajwa ZH, Wootton R, Warfield CA. Principles and Practice of Pain Medicine, 3e; 2016 Available at: http://accessanesthesiology.mhmedical.com/DownloadImage.aspx?image=/data/books/1845/bajpain3_c60_f008.png&sec=133689551&BookID=1845&ChapterSecID=133689394&imagename= Accessed: October 14, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved