Figure 1 Experimental protocol for the Rest (top) and Movement (bottom) groups. A one-minute rest period was applied between the two movement blocks in.

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Date of download: 5/30/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Robotic Devices as Therapeutic and Diagnostic Tools.

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Figure 1 Experimental protocol for the Rest (top) and Movement (bottom) groups. A one-minute rest period was applied between the two movement blocks in the Movement group. MEP = motor evoked potential. From: Movement Does Not Promote Recovery of Motor Output Following Acute Experimental Muscle Pain Pain Med. Published online May 19, 2017. doi:10.1093/pm/pnx099 Pain Med | © 2017 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

Figure 2 Mean of pain intensity rated on the 11-point numerical rating scale every 30 seconds from the time of hypertonic saline injection into the right extensor carpi radialis brevis muscle until each participant reported 0 for the Rest (filled circles; +SD) and Movement (open circles; –SD) groups. NRS = numeric rating scale. From: Movement Does Not Promote Recovery of Motor Output Following Acute Experimental Muscle Pain Pain Med. Published online May 19, 2017. doi:10.1093/pm/pnx099 Pain Med | © 2017 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

Figure 3 Mean (SD) motor evoked potential (MEP) amplitude at each time point in the Rest group (filled circles; –SD) and the Movement group (open circles; +SD). The gray box indicates the time of pain induced by hypertonic saline injection into the right extensor carpi radialis brevis muscle. Reduction in MEP amplitude from baseline (*P < 0.05). MEP = motor evoked potential. From: Movement Does Not Promote Recovery of Motor Output Following Acute Experimental Muscle Pain Pain Med. Published online May 19, 2017. doi:10.1093/pm/pnx099 Pain Med | © 2017 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

Figure 4 Motor evoked potential amplitude expressed as a proportion of baseline for each individual in the Rest (top) and Movement (bottom) groups at each time point. The gray box indicates the time of pain induced by hypertonic saline injection into the right extensor carpi radialis brevis muscle. Note that two participants in the Movement group exhibited facilitation immediately following the resolution of pain. MEP = motor evoked potential. From: Movement Does Not Promote Recovery of Motor Output Following Acute Experimental Muscle Pain Pain Med. Published online May 19, 2017. doi:10.1093/pm/pnx099 Pain Med | © 2017 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com