A consultand is an individual under evaluation for predicting his or her own future risk or the risk of his or her offspring. The arrow identifies the consultand. The 2 letter abbreviation with number (eg, Co 53) represents the diagnosis an individual received, followed by the age at the diagnosis. This pedigree meets Amsterdam II criteria,14 which include 3 relatives with a hereditary nonpolyposis colorectal cancer–associated tumor, such as colon cancer, endometrial cancer, ureteral cancer, cancer of the renal pelvis, ovarian cancer, stomach cancer, or small bowel cancer; 1 relative who is a first-degree relative of the other 2; cancers affecting at least 2 generations; and 1 or more cases diagnosed before aged 50 years. Source: Cancer, Family History, The Rational Clinical Examination: Evidence-Based Clinical Diagnosis Citation: Simel DL, Rennie D. The Rational Clinical Examination: Evidence-Based Clinical Diagnosis; 2016 Available at: http://jamaevidence.mhmedical.com/DownloadImage.aspx?image=/data/books/845/sim_ch20_f001.png&sec=68727584&BookID=845&ChapterSecID=61357507&imagename= Accessed: October 14, 2017 Copyright © 2017 American Medical Association. All rights reserved