BK polyomavirus-associated hemorrhagic cystitis among pediatric allogeneic bone marrow transplant recipients: Treatment response and evidence for nosocomial.

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Presentation transcript:

BK polyomavirus-associated hemorrhagic cystitis among pediatric allogeneic bone marrow transplant recipients: Treatment response and evidence for nosocomial transmission Minna Koskenvuo, Alexis Dumoulin, Irmeli Lautenschlager, Eeva Auvinen, Laura Mannonen, Veli-Jukka Anttila, Kirsi Jahnukainen, Ulla M. Saarinen-Pihkala, Hans H. Hirsch Journal of Clinical Virology Volume 56, Issue 1, Pages 77-81 (January 2013) DOI: 10.1016/j.jcv.2012.09.003 Copyright © 2012 Elsevier B.V. Terms and Conditions

Fig. 1 Plasma BKV loads and BKV-specific antibody responses. The cut-off value for positive antibody response is 0.1 EIA (OD492nm). Journal of Clinical Virology 2013 56, 77-81DOI: (10.1016/j.jcv.2012.09.003) Copyright © 2012 Elsevier B.V. Terms and Conditions

Fig. 2 Epidemiological studies. (A) Epidemic curve plot of BKV viremia. (B) Phylogenetic tree of the BKV variants. The tree reflects the combined analysis of the VP1 and NCCR sequences (total 585 nucleotides). The bar indicates the number of nucleotide changes per position. Journal of Clinical Virology 2013 56, 77-81DOI: (10.1016/j.jcv.2012.09.003) Copyright © 2012 Elsevier B.V. Terms and Conditions