Invasive lobular breast cancer and its variants: How special are they for systemic therapy decisions? Séverine Guiu, Anita Wolfer, William Jacot, Pierre.

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Presentation transcript:

Invasive lobular breast cancer and its variants: How special are they for systemic therapy decisions? Séverine Guiu, Anita Wolfer, William Jacot, Pierre Fumoleau, Gilles Romieu, Franck Bonnetain, Maryse Fiche Critical Reviews in Oncology / Hematology Volume 92, Issue 3, Pages 235-257 (December 2014) DOI: 10.1016/j.critrevonc.2014.07.003 Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Morphological aspects of classic and pleomorphic invasive lobular carcinoma. (A) Invasive lobular carcinoma, classic type. (B)–(D) Invasive pleomorphic lobular carcinoma: pleomorphic atypical nuclei (A); loss of E-cadherin expression (C) (E-cadherin is expressed in normal ductal cells); and Ki-67 immunostaining (D). Critical Reviews in Oncology / Hematology 2014 92, 235-257DOI: (10.1016/j.critrevonc.2014.07.003) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Flowchart of eligible studies. Critical Reviews in Oncology / Hematology 2014 92, 235-257DOI: (10.1016/j.critrevonc.2014.07.003) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions