Frequency and Markers of Precursor Lesions and Implications for the Pathogenesis of Testicular Germ Cell Tumors Finn Edler von Eyben, Marie Bjødstrup.

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Frequency and Markers of Precursor Lesions and Implications for the Pathogenesis of Testicular Germ Cell Tumors Finn Edler von Eyben, Marie Bjødstrup Jensen, Søren Høyer Clinical Genitourinary Cancer DOI: 10.1016/j.clgc.2017.08.010 Copyright © 2017 The Authors Terms and Conditions

Figure 1 Intratubular Seminoma (ITSE): (A) Immunohistochemistry (IHC) Showing Octamer-Binding Transcription Factor 4 (OCT4); (B) IHC Showing CD117; (C) IHC Not Showing CD30; and (D) Hematoxylin and Eosin Staining Showing the H&E Pattern Clinical Genitourinary Cancer DOI: (10.1016/j.clgc.2017.08.010) Copyright © 2017 The Authors Terms and Conditions

Figure 2 Microinvasive Germ Cell Tumor (MGCT): (A) Immunohistochemistry (IHC) Showing Octamer-Binding Transcription Factor 4 (OCT4+); (B) IHC Showing CD117+; (C) IHC Not Showing CD30; (D) Hematoxylin and Eosin Staining Showing the H&E Pattern Clinical Genitourinary Cancer DOI: (10.1016/j.clgc.2017.08.010) Copyright © 2017 The Authors Terms and Conditions

Figure 3 Frequency of Germ Cell Neoplasia in Situ (GCNIS) in Studies of Testes With Testicular Germ Cell Tumor Type II (TGCT). The Figure Summarizes Frequency as a Subtotal for Each of the Main TGCT Histologies and as a Total for Both Types Abbreviation: ES = effect size. Clinical Genitourinary Cancer DOI: (10.1016/j.clgc.2017.08.010) Copyright © 2017 The Authors Terms and Conditions

Figure 4 Frequency of Intratubular Seminoma (ITSE) in Studies of Testes With Testicular Germ Cell Tumor Type II (TGCT). The Figure Summarizes Frequency as a Subtotal for Each of the Main TGCT Histologies and as a Total for Both Types Abbreviation: ES = effect size. Clinical Genitourinary Cancer DOI: (10.1016/j.clgc.2017.08.010) Copyright © 2017 The Authors Terms and Conditions

Figure 5 Frequency of Intratubular Embryonal Carcinoma (ITEC) in Studies of Testes With Testicular Germ Cell Tumor Type II (TGCT). The Figure Summarizes Frequency as a Subtotal for Each of the Main TGCT Histologies and as a Total for Both Types Abbreviation: ES = effect size. Clinical Genitourinary Cancer DOI: (10.1016/j.clgc.2017.08.010) Copyright © 2017 The Authors Terms and Conditions

Figure 6 Frequency of Microinvasive Germ Cell Tumor (MGCT) in Studies of Testes With Testicular Germ Cell Tumor Type II (TGCT). The Figure Summarizes Frequency as a Subtotal for Each of the Main TGCT Histologies and as a Total for Both Types Abbreviation: ES = effect size. Clinical Genitourinary Cancer DOI: (10.1016/j.clgc.2017.08.010) Copyright © 2017 The Authors Terms and Conditions