Radiation Protection in the Intra- and Post-operative Diagnosis of the Sentinel Lymph Node J. Kopp H. Wengenmair Klinikum Augsburg, F.R.G.

Principle of the Sentinel Lymph Node Morton, Sem. Nucl. Med. 2000

Radiation Exposure from SLNE Surgeon

OP-Personnel (e.g. Anesthesiologist) Radiation Exposure from SLNE OP-Personnel (e.g. Anesthesiologist)

Radiation Exposure from SLNE Pathologist

Radiation Exposure of the Personnel from SLNE Summary => 1000 Patients per year: Dose still < 1mSv

Lymphatic Flow in the Mamma 0.1 - 1% 95%

Subdermal and intramammary Injection in SLN of Mamma-Carcinoma Dose to the Patient Effective Dose: 1mSv - 10mSv Mean 3.5mSv

Biodistribution of 99mTc-Nanocoll after intraprostatic Injektion Präsakral- und Pararektalregion A. u. V. iliaca externa A. u. V. iliaca interna Fossa obturatoria A. u. V. iliaca communis 20min p.i. 17h p.i. RVL LDR RVL. LDR

Exposure of the Patient from SLN-Diagnostic

Conclusion The dose to the personnel involved in intra- and post-operative diagnostic of the SLN is well beyond 1mSv Instruction and training of the personnel according to method and radiation protection is nevertheless highly recommended The dose to the patient is justified by the benefit from minimization of surgery and improved diagnostic of lymph node metastases