Gregor Mendel - A monk who studied peas in his garden and developed our basic understanding of heredity.
Allele Alternate forms of a gene Most traits have 2 alleles Ex. Mendel’s peas
Blue eye or brown eye allele
Heredity The transmission of characteristics from parents to offspring
Trait The visible character that shows Ex. Yellow pea or green pea
Genes A discrete unit of hereditary information located on a chromosome
Generations P1 Generation – The original parents F1 Generation – The first offspring (Children) F2 Generation – The offspring from the F1 gen. (grandchildren)
Law of segregation When gametes (sperm and egg) form, only one of the 2 possible genes for each trait will be in each gamete
Dominant vs. Recessive Dominant – The trait that is stronger or masks the other trait Recessive – The trait that is weaker or hidden
Dominant gene Black fur is dominant to white
If there are both a dominant and recessive traits together, only the dominant one appears
G g Genotype The genes an organism carries Ex: Gg = green (G) and yellow (g) genes G g
Phenotype How the genes are expressed (what it looks like) Ex: Gg has both green and yellow genes but the phenotype is green because green is dominant
G Homozygous Dominant Both Dominant Genes Present Genotype = GG Phenotype = Green GG G G
g Gg G Heterozygous 1 Dominant gene, 1 recessive gene present Genotype = Gg Phenotype = Green g Gg G
gg g g Homozygous Recessive Both recessive Genes Present Genotype = gg Phenotype = Yellow gg g g
Monohybrid cross Look at one single character
If we know the alleles of the parents, we can make predictions about the genetic traits of the offspring using A PUNNETT SQUARE! Draw a Punnett square Label 1 side with the genotype of one parent. Label the other side with the genotype of the other parent. Do the cross Describe genotypes including the possible percentages for the offspring Describe the phenotypes including the possible percentages for the offspring
Punnett Square Practice 1. Curly hair (H) is dominant to straight hair (h). Draw a punnett square crossing a heterozygous male (Hh) with a heterozygous female (Hh). Name all possible gentoypes and phenotypes and the percentages. H H H h h h Genotypes: HH: Hh: hh: Phenotypes: Curly: Straight: H h H H h h
Punnett Square Practice 2. Dimples (D) are dominant to not having dimples (d). Draw a punnett square crossing a homozygous dominant female (DD) with a homozygous recessive male (dd). Name all possible genotypes and phenotypes and the percentages. d d d d d d Genotypes: DD: Dd: dd: Phenotypes: Dimples: No Dimples: D D D D D D
Punnett Square Practice 3. Unattached earlobes (E) are dominant to attached earlobes (e). Draw a punnett square crossing a homozygous recessive female with a heterozygous male. Name all possible genotypes and phenotypes and percentages. e e Genotypes: EE: Ee: ee: Phenotypes: Attached: Unattached: E e Ee Ee ee ee
Punnett Square Practice 4. Having freckles (F) is dominant to not having freckles (f). Draw a Punnett square crossing a heterozygous female with a homozygous dominant male. Name all possible genotypes and phenotypes and percentages. F f Genotypes: FF: 50% Ff: 50% PhenotypesFreckles: 100% F F FF Ff
Punnett Square Practice i i 5. Immunity to poison ivy is dominant to being susceptible to getting poison ivy. Draw a punnett square crossing a homozygous recessive female with a homozygous dominant male. Name all possible genotypes and phenotypes and percentages. Genotypes: Ii: 100% PhenotypesImmunity: 100% I I Ii Ii
Punnett Square Practice 6. A widow’s peak is dominant to a normal hairline. Draw a punnett square crossing a heterozygous female with a heterozygous male. Name all possible genotypes and phenotypes and percentages. W w Genotypes: WW: 25% Ww: 50% ww: 25% PhenotypesImmunity: Widows peak: 75% Normal: 25% W w WW Ww Ww ww
Cases in Genetics with Filbert the Frog and Friends
Dihybrid Punnett Squares S: smooth s: rough Y: yellow y: green Dihybrid Punnett Squares Genotypes: Phenotypes: SSYY: 1/16 SSYy: 2/16 SSyy: 1/16 SsYY: 2/16 SsYy: 4/16 Ssyy: 2/16 ssYY: 1/ 16 ssYy: 2/16 ssyy: 1/16 Smooth Yellow: 9/16 Rough Yellow: 3/16 Smooth green: 3/16 Rough green: 1/16
Now try to make one… Genotypes: Phenotypes: BBSS: 1/16 BBSs: 2/16 B = black fur b = brown fur S = short fur s = long fur Now try to make one… Genotypes: Phenotypes: BBSS: 1/16 BBSs: 2/16 BBss: 1/16 BbSS: 2/16 BbSs: 4/16 Bbss: 2/16 bbSS: 1/16 bbSs: 2/16 bbss: 1/16 BBSS BBSs BbSS BbSs BBSs BBss BbSs Bbss BbSS BbSs bbSS bbSs BbSs Bbss bbSs bbss Black, Short: 9/16 Brown, Short: 3/16 Black, Long: 3/16 Brown, Long: : 1/16
Try this one: BBSs vs. bbSs B = black fur b = brown fur S = short fur s = long fur Try this one: BBSs vs. bbSs Genotypes: Phenotypes:
BBSs vs. bbSs BS Bs bS bs
Try this one: BBSs vs. bbSs B = black fur b = brown fur S = short fur s = long fur Try this one: BBSs vs. bbSs Genotypes: Phenotypes: bS bs bS bs BbSS: 4/16 BbSs: 8/16 Bbss: 4/16 BS Bs BbSS BbSs BbSS BbSs BbSs Bbss BbSs Bbss BbSS BbSs BbSS BbSs Black, Short: 12/16 Black, long: 4/16
Homework: Complete a dihybrid punnett square using this cross: TtRR x TTrr. Tall (T) is dominant to short (t) and Red (R) is dominant to pink (r). Find the genotype and phenotype percentages.