Prospective Study of the Effect of the 21-Gene Assay on Adjuvant Clinical Decision- Making in Japanese Women With Estrogen Receptor-Positive, Node-Negative,

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Prospective Study of the Effect of the 21-Gene Assay on Adjuvant Clinical Decision- Making in Japanese Women With Estrogen Receptor-Positive, Node-Negative, and Node-Positive Breast Cancer Hideko Yamauchi, Chizuko Nakagawa, Hiroyuki Takei, Calvin Chao, Carl Yoshizawa, Hiroshi Yagata, Atsushi Yoshida, Naoki Hayashi, Susanne Hell, Seigo Nakamura Clinical Breast Cancer Volume 14, Issue 3, Pages 191-197 (June 2014) DOI: 10.1016/j.clbc.2013.10.017 Copyright © 2014 The Authors Terms and Conditions

Figure 1 Recommendation for Adjuvant Chemotherapy Pre- and Post-Assay Abbreviation: RS = Recurrence Score result. ∗Regardless of nodal status. Clinical Breast Cancer 2014 14, 191-197DOI: (10.1016/j.clbc.2013.10.017) Copyright © 2014 The Authors Terms and Conditions

Figure 2 Change in Physicians' Confidence After The 21-Gene Assay Abbreviation: RS = Recurrence Score result. ∗Answers to the question (post-RS): “I am more confident in my treatment recommendation.” Clinical Breast Cancer 2014 14, 191-197DOI: (10.1016/j.clbc.2013.10.017) Copyright © 2014 The Authors Terms and Conditions