American Heart Journal

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American Heart Journal Rationale and design of POPular-TAVI: antiPlatelet therapy fOr Patients undergoing Transcatheter Aortic Valve Implantation Vincent Johan Nijenhuis, MD, Naoual Bennaghmouch, MD, Mariella Hassell, MD, Jan Baan, MD, PhD, Jan Peter van Kuijk, MD, PhD, Pierfrancesco Agostoni, MD, PhD, Arnoud van ‘t Hof, MD, PhD, Peter C. Kievit, MD, PhD, Leo Veenstra, MD, Pim van der Harst, MD, PhD, Ad F.M. van den Heuvel, MD, PhD, Peter den Heijer, MD, PhD, Johannes C. Kelder, MD, PhD, Vera H. Deneer, PharmD, PhD, Frank van der Kley, MD, Francesco Onorati, MD, PhD, Jean Philippe Collet, MD, PhD, Francesco Maisano, MD, PhD, Azeem Latib, MD, PhD, Kurt Huber, MD, PhD, Pieter R. Stella, MD, PhD, Jurrien M. ten Berg, MD, PhD American Heart Journal Volume 173, Pages 77-85 (March 2016) DOI: 10.1016/j.ahj.2015.11.008 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure POPular TAVI study design. After inclusion, patients are stratified according to the presence or absence of OAC therapy. The day before TAVI, patients are randomized in a 1:1 manner to clopidogrel or no clopidogrel in addition to aspirin (cohort A) or OAC (cohort B). American Heart Journal 2016 173, 77-85DOI: (10.1016/j.ahj.2015.11.008) Copyright © 2015 Elsevier Inc. Terms and Conditions