Fluid/blood warmer for treating roadside trauma Submitted by Name: Mark McEwen, Anne-Louise Smith Affiliation: CED Collaborator National association (if exists): SMBE, Society of Medical & Biological Engineering Location: Adelaide, South Australia E-mail address for contact: anne-louise.smith@sa.gov.au

Country Estimates in Brief Please fill the statistics you can find Population Australia 24M South Australia 1.7M Population Growth Rate Australia 1.3% South Australia 0.7% Life Expectancy at Birth 80.3 male, 84.4 female Infant Mortality Rate 3/1000 live births under 1 yr Number of Health Centers in Country 747 public hospitals 612 private hospitals Total Expenditure on Health as % of GDP 9.1% Global CE / HTM Success Stories

Global CE / HTM Success Stories Country's Health Technology Program Fluid/blood warmer for roadside trauma Retrieval patients are often in shock, hypotensive and hypothermic (<37ºC). Treatment requires rapid restoration of blood volume with transfusion of donor blood and/or clear fluids. The Transfusion Service clinicians determined there was a need for trauma/retrieval patients to receive these fluids at close to body temperature to reduce the risk of hypothermia. There is approximately 0.51ºC temperature drop per litre of 4ºC fluid infused into a 70 kg patient starting at 37ºC No devices could be found to meet the need so a device was developed by Biomedical Engineering. January 2016 Global CE / HTM Success Stories

Country's Health Technology Program Next Steps for Success Story The Intravenous Fluid/Blood Warmer was developed Uses latent heat of fusion as an energy source. Initial validation was performed to ensure heating is adequate for infusion whilst non injurious to red cell products (results published BMC Emergency Medicine) Useful requirements Blood: Warm at least 2 units from 4ºC to >30ºC at flow rate of 50 mL/min with single device Gelofusine (fluid): Warm at least 1L from 20ºC to >30ºC at flow rate of 150 mL/min with single device Device: Convenient size, weight and volume No external power source required, stable over range of temperatures, long life, reliable and fast acting heat January 2016 Global CE / HTM Success Stories

Conclusions and Action Plan Clinical trial in progress Patients receiving planned blood transfusions No adverse effect on patients or blood test results Useability trial Emergency Department & Intensive Care Unit nurses using the warmer, to determine the best operating method and most effective instructions Commercialisation The device has been licensed to a specialist plastics fabricator, partnering with an IV set manufacturer Production scheduled when trials completed January 2016 Global CE / HTM Success Stories