High dietary salt decreases antioxidant defenses in the liver of fructose-fed insulin- resistant rats Waleska Claudia Dornas, Wanderson Geraldo de Lima,

Slides:

Advertisements

Similar presentations

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

Advertisements

Portuguese traditional sausages: different types, nutritional composition, and novel trends Cláudia Marcos, Cláudia Viegas, André M. de Almeida, Maria.

Effects of pre- and postnatal protein deprivation and postnatal refeeding on atrial natriuretic peptide (ANP) granules of auricular cardiocytes Eliane.

Maternal protein restriction during pregnancy and lactation in rats imprints long-term reduction in hepatic lipid content selectively in the male offspring

Effects of biotin deficiency on pancreatic islet morphology, insulin sensitivity and glucose homeostasis Elena Larrieta, Maria Luisa Lazo de la Vega-Monroy,

Effects of Myrtus communis extract treatment in bile duct ligated rats

Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract Gregory J.

François Tremblay, Jenna Waterhouse, Janette Nason, Wilhelmina Kalt

Wild blueberry (Vaccinium angustifolium) consumption improves inflammatory status in the obese Zucker rat model of the metabolic syndrome Stefano Vendrame,

Prevalence of subclinical hypercortisolism in type 2 diabetic patients from the Rio de Janeiro Type 2 Diabetes Cohort Study Denise S. Costa, Flavia L.

Volume 36, Issue 12, Pages (December 2016)

Effector/memory T cells of the weanling mouse exhibit Type 2 cytokine polarization in vitro and in vivo in the advanced stages of acute energy deficit

Xiaodong Zhou, Anne M. Smith, Mark L. Failla, Kristina E

(−)-Epicatechin reduces blood pressure increase in high-fructose-fed rats: effects on the determinants of nitric oxide bioavailability Maria C. Litterio,

Dietary whey protein lowers serum C-peptide concentration and duodenal SREBP-1c mRNA abundance, and reduces occurrence of duodenal tumors and colon aberrant.

Venkata J. Adapala, Sunday A. Adedokun, Robert V. Considine, Kolapo M

Polyphenols in brewed green tea inhibit prostate tumor xenograft growth by localizing to the tumor and decreasing oxidative stress and angiogenesis Susanne.

Maternal taurine supplementation attenuates maternal fructose-induced metabolic and inflammatory dysregulation and partially reverses adverse metabolic.

High-protein diets prevent steatosis and induce hepatic accumulation of monomethyl branched-chain fatty acids Sonia C. Garcia Caraballo, Tine M. Comhair,

Diets enriched in trans-11 vaccenic acid alleviate ectopic lipid accumulation in a rat model of NAFLD and metabolic syndrome M. Miriam Jacome-Sosa, Faye.

Volume 32, Issue 9, Pages (September 2012)

The functional effect of soybean extract and isolated isoflavone on myocardial infarction and ventricular dysfunction Ana C. Miguez, Julio C. Francisco,

Chun-Ching Shih, Cheng-Hsiu Lin, Wei-Li Lin

You-Lin Tain, Kay L.H. Wu, Wei-Chia Lee, Steve Leu, Julie Y.H. Chan

Dietary extra virgin olive oil polyphenols supplementation modulates DSS-induced chronic colitis in mice Susana Sánchez-Fidalgo, Ana Cárdeno, Marina.

Extra-virgin olive oil diet and mild physical activity prevent cartilage degeneration in an osteoarthritis model: an in vivo and in vitro study on lubricin.

Protective effects of hydroxytyrosol-supplemented refined olive oil in animal models of acute inflammation and rheumatoid arthritis S. Silva, B. Sepodes,

Trans fat intake lowers total cholesterol and high-density lipoprotein cholesterol levels without changing insulin sensitivity index in Wistar rats Zhiliang.

Volume 32, Issue 7, Pages (July 2016)

Creatine supplementation prevents fatty liver in rats fed choline-deficient diet: a burden of one-carbon and fatty acid metabolism Rafael Deminice, Gabriela.

Different effects of catechin on angiogenesis and inflammation depending on VEGF levels Rita Negrão, Raquel Costa, Delfim Duarte, Tiago Taveira Gomes,

Characterization of TGF-β expression and signaling profile in the adipose tissue of rats fed with high-fat and energy-restricted diets Bernardo Sousa-Pinto,

Maharshi Bhaswant, Hemant Poudyal, Lindsay Brown

Nutritional therapy for nonalcoholic fatty liver disease

Fig. 1. Body growth and leptin responsivity in young CPO and CTR mice

Volume 35, Issue 6, Pages (June 2015)

Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes Mandana Pahlavani, Fitia Razafimanjato,

Vitamin E does not prevent bone loss and induced anxiety in rats with ligature-induced periodontitis Rosimary de Sousa Carvalho, Carolina Melo de Souza,

Volume 123, Issue 1, Pages (July 2002)

Volume 60, Issue 6, Pages (December 2001)

Volume 122, Issue 2, Pages (February 2002)

Volume 122, Issue 2, Pages (February 2002)

Reactive oxygen species in the normal and acutely injured liver

Volume 24, Issue 2, Pages (June 2017)

Volume 120, Issue 5, Pages (April 2001)

Omega-3 fatty acids decreases oxidative stress, tumor necrosis factor-alpha, and interleukin-1 beta in hyperthyroidism-induced hepatic dysfunction rat.

Volume 117, Issue 4, Pages (October 1999)

Volume 129, Issue 5, Pages (November 2005)

Volume 132, Issue 1, Pages (January 2007)

Selective early increases of bronchoalveolar CD8+ lymphocytes in a LEW rat model of hypersensitivity pneumonitis Hal B. Richerson, MD, J.Daniel Coon,

Neuroprotection following mild hypothermia after spinal cord ischemia in rats Takeshi Saito, PhD, Shino Saito, MD, Hiroshi Yamamoto, MD, PhD, Masanori.

Volume 114, Issue 1, Pages (January 1998)

Volume 119, Issue 6, Pages (December 2000)

Volume 39, Issue 4, Pages (October 2003)

Volume 60, Issue 6, Pages (December 2001)

Resveratrol increases serum adiponectin level and decreases leptin and insulin level in an experimental model of hypercholesterolemia A. Jimoh, Y. Tanko,

Volume 122, Issue 2, Pages (February 2002)

Vitamin D reduces high-fat diet induced weight gain and C-reactive protein, increases interleukin-10, and reduces CD86 and caspase-3 Asmaa M.S. Gomaa,

Folic acid protects against lead acetate-induced hepatotoxicity by decreasing NF-κB, IL- 1β production and lipid peroxidation mediataed cell injury Eman.

Antidiabetic Effects of IGFBP2, a Leptin-Regulated Gene

Samina Hyder Haq, Abir Abdullah AlAmro Clinical Nutrition Experimental

Volume 59, Issue 2, Pages (August 2013)

Carotid plaque instability and ischemic symptoms are linked to immaturity of microvessels within plaques Benjamin J. Dunmore, PhD, Mark J. McCarthy,

Divergent roles of superoxide and nitric oxide in reduced-size liver ischemia and reperfusion injury: Implications for partial liver transplantation

Volume 124, Issue 1, Pages (January 2003)

Volume 9, Issue 6, Pages (June 2009)

Exercise training plays cardioprotection through the oxidative stress reduction in obese rats submitted to myocardial infarction Viviane A. Barbosa,

Volume 124, Issue 5, Pages (May 2003)

Volume 72, Issue 11, Pages (December 2007)

Volume 6, Issue 6, Pages (December 2007)

Presentation transcript:

High dietary salt decreases antioxidant defenses in the liver of fructose-fed insulin- resistant rats Waleska Claudia Dornas, Wanderson Geraldo de Lima, Rinaldo Cardoso dos Santos, Joyce Ferreira da Costa Guerra, Melina Oliveira de Souza, Maísa Silva, Lorena Souza e Silva, Mirla Fiuza Diniz, Marcelo Eustáquio Silva Journal of Nutritional Biochemistry Volume 24, Issue 12, Pages 2016-2022 (December 2013) DOI: 10.1016/j.jnutbio.2013.06.006 Copyright © 2013 Elsevier Inc. Terms and Conditions

Fig. 1 Food, fluid, caloric intake and serum leptin of experimental rats. Symbols represent the animals in scatter plots to each group. Different letters indicate significant differences at P<.05 by one-way ANOVA followed by Tukey’s test. Control diet (CON); high-salt diet (HS); high-fructose diet (HF); high-fructose and salt (HFS) diet for 10 weeks after previous treatment for a period of 10 weeks with HF. Journal of Nutritional Biochemistry 2013 24, 2016-2022DOI: (10.1016/j.jnutbio.2013.06.006) Copyright © 2013 Elsevier Inc. Terms and Conditions

Fig. 2 (A-D) Representative photomicrographs H&E staining of liver sections of experimental rats. Hepatocytes abnormalities were not observed in the CON group (A); note hyperemic vessels (arrowhead) and normal parenchyma appearance in the HS group (B); aspect of macrovesicular steatosis in the HF group (C). Note hepatocytes with a large negative image in the cytoplasm with nucleus displaced into the periphery of the cell, large fat globule in most cases (white arrow); aspect of microvesicular steatosis in the HFS group (D). Note cells with small cytoplasmic vacuoles without displaced nucleus (black arrow) magnification ×440. Grade of liver steatosis of rats in experimental groups (E). Values (medianne, n=8–11) (*P<.05 vs. control rats). Journal of Nutritional Biochemistry 2013 24, 2016-2022DOI: (10.1016/j.jnutbio.2013.06.006) Copyright © 2013 Elsevier Inc. Terms and Conditions

Fig. 3 Antioxidant defenses and oxidative stress in the liver of experimental rats. Different letters indicate significant differences at P<.05 by one-way ANOVA followed by Tukey’s test. Journal of Nutritional Biochemistry 2013 24, 2016-2022DOI: (10.1016/j.jnutbio.2013.06.006) Copyright © 2013 Elsevier Inc. Terms and Conditions