Clinical Translational Science Award Applications & Family Medicine

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Presentation transcript:

Clinical Translational Science Award Applications & Family Medicine Bernard Ewigman, MD Freddy Chen, MD Lloyd Michener, MD October 17, 2006

Clinical Translational Science Awards (CTSA) Introduction to CTSA & Univ of Chicago Experience -- Bernard Ewigman NAPCRG & ADFM (Department Chairs) Surveys -- Freddy Chen Duke University Experience, General Themes & Challenges -- Lloyd Michener Discussion -- All participants

Clinical Translational Science Awards (CTSA) $100 million awarded to 12 Academic Health Centers (AHCs) plus 52 Planning Grants By 2012, $500 million awarded to 60 AHCs Purpose: Part of the National Institutes of Health (NIH) Roadmap Plan

CTSA Purpose “First systematic change to clinical research in 50 years.” “Discovery engines..applying medical advances to real world practice.” “…new approaches to reaching underserved populations.” “….to insure that medical advances are reaching those who need them.” NIH Director Elias A. Zerhouni, M.D. October 3, 2006

CTSA Expectations Create new Institute, Center or Department Create new discipline of “Clinical Translational Science”. Multi-disciplinary Folds in the General Clinical Research Centers and K-12 (post-graduate training) awards

CTSA Funding $4 million/per year x 5 years $6 million/per year x 5 years if Pediatrics and Community Engagement is included. Indirect costs come out of the total K-12 training costs come out of the total Reminder (~$2 million) allocated to 10 required components U-54 mechanism—all funding for infrastructure development

University of Chicago CTSA Proposed Institute for Translational Science Four Divisions: Core Resources, Clinical Trials, Training and Community Translational Science Divisions (CTSD) Ewigman (Family Medicine)– Director of CTSD Hickner – (Co-Director of Practice Based Research Programs – within CTSD)

Practice Based Research Networks Advocate Health Systems 2,700 physicians 5 community based hospitals 2 family medicine residency programs New network, but strong track record ACCESS Community Health Networks Largest CHC in the US 48 health centers 1 family medicine residency program 4 active, 2 planned family medicine research studies

Univ of Chicago Review Score = 197 (possible range 100 to 500) Outstanding (2 sections) Excellent (10 sections) Very Good to Excellent (4 sections) Including “Community Engagement” Very Good (1 section) “Training”

Univ of Chicago Review General criticisms: Not well integrated across components Did not define obstacles well Lack epidemiology and clinical epidemiology Lack of training of community participants Lack of engagement of the community in decision making