Multimodal Neural Monitoring Group C Kathy Dai, Brett Dixon, Wassim Khalil, Kylie McClanahan, Cody Phillips
people die of Heart Disease per year = 1 in 4 Deaths 610,000 people die of Heart Disease per year = 1 in 4 Deaths
Problem Coronary Artery Bypass Graft Surgery Neurological Injuries Cardiopulmonary Bypass Neurological Injuries Loss of White Matter Current practices to monitor the brain in cardiac surgery Post-oximetry Urinal catheter
Objective Brain “Cap” CSCE Cerebral Activity (EEG) Oxygen Content Cerebral Blood Flow Velocity System Blood Pressure Temperature CSCE Easily-Readable Data User-Friendly Interface
Background and Previous Work Relevant technologies: Cardiopulmonary Bypass (CPB) Electroencephalogram (EEG) Near-infrared spectroscopy (NIRS) Previous research: Neurocognitive dysfunction is prevalent Monitoring the cerebral cortex can positively affect outcome NIRS data Oxygenation Blood flow Cerebral temperature
Design Requirements and Design Goals High Level Architecture What the UI should display UI will be used as alert UI will be used for postoperative investigations High Level Architecture Real time regional monitoring of brain blood flow, oxygenation, temperature, electrophysiological activity if oxygenation falls below a certain threshold. More advanced algorithms could possibly correlate multiple data points and make a comprehensive assessment of overall brain condition. Data will be stored in the PC used to be retrieved again for investigation
Deliverables Design Document Data Information Software Releases “Cap” design Hardware and Software used Data Information How we analyzed the data to establish a normal Software Releases Multiple updates after initial deployment to get feedback from mentors and BMEGs Test Cases Well documented reports of continuous testing Final Report Wrap-up of project in its entirety