Photodiagnosis and Photodynamic Therapy

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Photodiagnosis and Photodynamic Therapy Fluorescence intensity and bright spot analyses using a confocal microscope for photodynamic diagnosis of brain tumors Takeshi Yoneyama, Tetsuyo Watanabe, Hiroyuki Kagawa, Yutaka Hayashi, Mitsutoshi Nakada Photodiagnosis and Photodynamic Therapy Volume 17, Pages 13-21 (March 2017) DOI: 10.1016/j.pdpdt.2016.11.002 Copyright © 2016 Elsevier B.V. Terms and Conditions

Fig. 1 Confocal microscope system. Photodiagnosis and Photodynamic Therapy 2017 17, 13-21DOI: (10.1016/j.pdpdt.2016.11.002) Copyright © 2016 Elsevier B.V. Terms and Conditions

Fig. 2 Fluorescence intensity analysis from the captured image. Photodiagnosis and Photodynamic Therapy 2017 17, 13-21DOI: (10.1016/j.pdpdt.2016.11.002) Copyright © 2016 Elsevier B.V. Terms and Conditions

Fig. 3 Probability that the intensity of the specimen exceeds that of the dark image. Photodiagnosis and Photodynamic Therapy 2017 17, 13-21DOI: (10.1016/j.pdpdt.2016.11.002) Copyright © 2016 Elsevier B.V. Terms and Conditions

Fig. 4 Bright spot size and spot number analysis. Photodiagnosis and Photodynamic Therapy 2017 17, 13-21DOI: (10.1016/j.pdpdt.2016.11.002) Copyright © 2016 Elsevier B.V. Terms and Conditions

Fig. 5 Comparison between confocal microscopy image and H&E image on the specimen from tumor area. Photodiagnosis and Photodynamic Therapy 2017 17, 13-21DOI: (10.1016/j.pdpdt.2016.11.002) Copyright © 2016 Elsevier B.V. Terms and Conditions

Fig. 6 Comparison between confocal microscopy image and H&E image on the specimen from boundary area. Photodiagnosis and Photodynamic Therapy 2017 17, 13-21DOI: (10.1016/j.pdpdt.2016.11.002) Copyright © 2016 Elsevier B.V. Terms and Conditions

Fig. 7 Fluorescence intensity analysis. Photodiagnosis and Photodynamic Therapy 2017 17, 13-21DOI: (10.1016/j.pdpdt.2016.11.002) Copyright © 2016 Elsevier B.V. Terms and Conditions

Fig. 8 Spot size analysis on the specimen from boundary area. Photodiagnosis and Photodynamic Therapy 2017 17, 13-21DOI: (10.1016/j.pdpdt.2016.11.002) Copyright © 2016 Elsevier B.V. Terms and Conditions