Brain Tumour Bank at Institute of Neurology Professor Sebastian Brandner Chair of Neuropathology Division of Neuropathology and Department of Neurodegenerative Disease Institute of Neurology Queen Square London WC1N 3BG Phone: +44 (0)20 3448 4435 Secretary: +44 (0)20 3448 4234 Fax: +44 (0)20 3448 4486 email: s.brandner@ucl.ac.uk http://www.ucl.ac.uk/ion/divisions/neuropathology/themes/brain

Aims of Brain Tumour Bank To collect specimens for research and to derive cell lines from living tumour cells. This collection will be used for brain cancer research and material can be made available to researchers at UCL, in the UK and internationally

Brain Tumour Bank at IoN The brain tumour bank was established in 2008 Currently banking 20 samples every month, and one cell line is successfully established every week. In parallel, all gliomas are being characterised by state of the art molecular pathology tests, which allows us to correlate clinical findings, pathological features and the growth and biological behaviour of these tumours. The availability of these tests is also essential for a selection of defined tumour subgroups for research projects.

Project example. Modelling intrinsic brain tumours: Oncogenic signalling in neural stem cells in grafted brain tumour cells

Summary of range of brain tumour types in IoN bank. Total samples 670

Contact for further information Professor Sebastian Brandner Chair of Neuropathology Division of Neuropathology and Department of Neurodegenerative Disease Institute of Neurology Queen Square London WC1N 3BG Phone: +44 (0)20 3448 4435 Secretary: +44 (0)20 3448 4234 Fax: +44 (0)20 3448 4486 email: s.brandner@ucl.ac.uk