A Study of GWAS-Supported Variants of rs9943582 in a Chinese Han Population with Ischemic Stroke: No Associations with Disease Onset and Clinical Outcomes

Slides:

Advertisements

Similar presentations

Epileptic Ictal Hyperperfusion on Arterial Spin Labeling Perfusion and Diffusion- Weighted Magnetic Resonance Images in Posterior Reversible Encephalopathy.

Advertisements

The IL-33-ST2L Pathway Is Associated with Coronary Artery Disease in a Chinese Han Population Xin Tu, Shaofang Nie, Yuhua Liao, Hongsong Zhang, Qian.

Prognostic Value of Morning Blood Pressure Surge in Clinical Events: A Meta-analysis of Longitudinal Studies Jun-Chao Xie, Han Yan, Yan-Xin Zhao, PhD,

Evaluation of the Efficacy and Safety of Direct Oral Anticoagulants in Japanese Patients—Analysis of Pharmaceuticals and Medical Devices Agency Data

Relationship between Diffusion Tensor Fractional Anisotropy and Motor Outcome in Patients with Hemiparesis after Corona Radiata Infarct Tetsuo Koyama,

Effect of contrast material (Levovist) infusion on peak systolic velocity in middle cerebral artery using transcranial color-coded duplex sonography

Outcomes of Primary Squamous Cell Carcinoma of Major Salivary Glands Treated by Surgery With or Without Postoperative Radiotherapy Lina Wang, MD, Hao.

Variant Type of Posterior Reversible Encephalopathy Syndrome with Diffuse Cerebral White Matter and Brainstem Involvement Associated with Intracranial.

Society of Thoracic Surgeons 2008 cardiac risk models predict in-hospital mortality of heart valve surgery in a Chinese population: A multicenter study

Winter birth in inner-city asthmatic children is associated with increased food allergen sensitization risk J. Andrew Bird, MD, Julie Wang, MD, Cynthia.

Asthma Phenotypes Defined From Parameters Obtained During Recovery From a Hospital-Treated Exacerbation Rihuang Qiu, MD, Jiaxing Xie, MD, PhD, Kian Fan.

Inelastic bandages maintain their hemodynamic effectiveness over time despite significant pressure loss Giovanni Mosti, MD, Hugo Partsch, MD, PhD Journal.

Reduced endothelial progenitor cells in extracranial arterial stenosis but not intracranial arterial stenosis Zhixin Huang, MD, PhD, Xiaohao Zhang, MD,

Volume 3, Issue 2, Pages (June 2017)

Valentina Cannone, MD, PhD, Alessia Buglioni, MD, S

Association of functional genetic variants of CTLA4 with reduced serum CTLA4 protein levels and increased risk of idiopathic recurrent miscarriages Maneesh.

Pain during bone marrow aspiration: prevalence and prevention

Skills training after night shift work enables acquisition of endovascular technical skills on a virtual reality simulator Peter A. Naughton, MD, Rajesh.

Jason W. Christie, MD, Thomas D. Conlee, MD, Timothy E

John W. Steinke, PhD, Spencer C. Payne, MD, M

Gender, power and leadership: the effect of a superior's gender on respiratory therapists’ ability to challenge leadership during a life-threatening emergency

Dietary Fiber Intake Reduces Risk for Gastric Cancer: A Meta-analysis

Association of the CHRNA3 Locus with Lung Cancer Risk and Prognosis in Chinese Han Population Xiaomin Niu, MD, Zhiwei Chen, MD, PhD, Shengping Shen,

TIA for the Internist The American Journal of Medicine

Relative importance of aneurysm diameter and body size for predicting abdominal aortic aneurysm rupture in men and women Ruby C. Lo, MD, Bing Lu, MD,

Identification of susceptibility SNPs in IL10 and IL23R-IL12RB2 for Behçet's disease in Han Chinese Hongsong Yu, PhD, Minming Zheng, MS, Lijun Zhang,

Assessment of mitral annuloplasty ring by cardiac computed tomography: Correlation with echocardiographic parameters and comparison between two different.

Hsin Hsu Wu, MD, Chang Fu Kuo, MD, PhD, I

Fast Protocol for Treating Acute Ischemic Stroke by Emergency Physicians Iiro Heikkilä, MD, Hanna Kuusisto, MD, PhD, Markus Holmberg, MD, Ari Palomäki,

Daniel E. Weiner, MD, MS American Journal of Kidney Diseases

The role of tissue factor in patients undergoing open repair of ruptured and nonruptured abdominal aortic aneurysms Simon D. Hobbs, MBChB, Paul Haggart,

Prolonged gonadotropin-releasing hormone agonist therapy reduced expression of nitric oxide synthase in the endometrium of women with endometriosis and.

Andrea M. Steely, Peter W. Callas, Salvatore T. Scali, Philip P

Prehypertension and Incidence of ESRD: A Systematic Review and Meta-analysis Yuli Huang, MD, Xiaoyan Cai, MD, Jianyu Zhang, MD, Weiyi Mai, MD, PhD, Sheng.

The progression of chronic kidney disease: A 10-year population-based study of the effects of gender and age B.O. Eriksen, O.C. Ingebretsen Kidney International

Variants in the Eppin gene show association with semen quality in Han-Chinese population Xinliang Ding, Jie Zhang, Zenghui Bian, Yankai Xia, Chuncheng.

Challenges in analysis and interpretation of cost data in vascular surgery Kevin Mani, MD, Jonas Lundkvist, RPh, PhD, Lars Holmberg, MD, PhD, Anders Wanhainen,

Volume 61, Issue 6, Pages (June 2002)

Common 677C→T mutation of the 5,10-methylenetetrahydrofolate reductase gene affects follicular estradiol synthesis Stephanie Hecht, Roman Pavlik, Peter.

Reduced pleural drainage, length of stay, and readmissions using a modified Fontan management protocol Nancy A. Pike, PhD, Carol A. Okuhara, MN, Joy.

The Effect of Resistance Exercise to Augment Long-term Benefits of Intradialytic Oral Nutritional Supplementation in Chronic Hemodialysis Patients Jie.

Impact of acute cerebral ischemic lesions and their volume on the revascularization outcome of symptomatic carotid stenosis Rodolfo Pini, MD, Gianluca.

Age- and disease-related variations in B-type natriuretic peptide response after pediatric cardiac surgery Massimiliano Cantinotti, MD, Aldo Clerico,

Bradley A. Ford, Daniel W. Coyne, Charles S. Eby, Mitchell G. Scott

Genetic Investigation of Quantitative Traits Related to Autism: Use of Multivariate Polygenic Models with Ascertainment Adjustment Yun Ju Sung, Geraldine.

Microembolization is associated with transient cognitive decline in patients undergoing carotid interventions Elizabeth Hitchner, MA, Brittanie D. Baughman,

Women with spontaneous 46,XX primary ovarian insufficiency (hypergonadotropic hypogonadism) have lower perceived social support than control women Susan.

FIGURE 1 Flow chart showing the number of individuals at each stage of the experiment. Among the 61 dyads who ... FIGURE 1 Flow chart showing the number.

Anneke P. Bech, MD, Jack F.M. Wetzels, PhD, Tom Nijenhuis, PhD

Quantitative Computed Tomography Analysis, Airflow Obstruction, and Lung Cancer in the Pittsburgh Lung Screening Study David O. Wilson, MD, MPH, Joseph.

Marc A. Bailey, BSc, MRCS, Patrick A

Volume 76, Issue 8, Pages (October 2009)

Testosterone levels in pregnant women correlate with the insulin response during the glucose tolerance test Anuja Dokras, M.D., Ph.D., Robert Z Spaczynski,

Diastolic function predicts survival after renal revascularization

Diminished intrafollicular estradiol levels in in vitro fertilization cycles from women with reduced ovarian response to recombinant human follicle-stimulating.

Comparative Superiority of ACE Inhibitors Over Angiotensin Receptor Blockers for People With CKD: Does It Matter? Dimitris Mavridis, PhD American Journal.

Orhan Bukulmez, M. D. , Bruce R. Carr, M. D. , Kathleen M. Doody, M. D

Efficacy of intrauterine inseminations as a training modality for performing embryo transfer in reproductive endocrinology and infertility fellowship.

Changes in baroreceptor sensitivity after eversion carotid endarterectomy Serdar Demirel, MD, Nicolas Attigah, MD, Hans Bruijnen, MD, Laura Macek, MD,

P Combined Molecular and Radiological Evaluation Unveils Three Subtypes of Disease Progression to a Third Generation EGFR TKI Y. Zhang, Q. Zhou,

Prevalence of and risk factors for peripheral arterial disease in the patients with hypertension among Han Chinese XiaoMin Yang, MD, Kai Sun, PhD, WeiLi.

K. W. Marshall, M. D. , Ph. D. , F. R. C. S. (C), H. Zhang, M. D. , Ph

A randomized trial of the effect of low dose epinephrine infusion in addition to tranexamic acid on blood loss during total hip arthroplasty Ø. Jans,

Use of a high-fidelity simulator to develop testing of the technical performance of novice anaesthetists† F.C. Forrest, M.A. Taylor, K. Postlethwaite,

Fibrinogen plasma concentration before delivery is not associated with postpartum haemorrhage: a prospective observational study O. Karlsson, A. Jeppsson,

The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington Disease Jae Whan Keum, Aram Shin, Tammy Gillis, Jayalakshmi Srinidhi.

Methylenetetrahydrofolate reductase C677T polymorphism and the risk of unexplained recurrent pregnancy loss: A meta-analysis Aiguo Ren, M.D, Ph.D., Juan.

Divergent effects of the 677C>T mutation of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene on ovarian responsiveness and anti-Müllerian hormone.

A Population-Based Study of Acquired Bilateral Nevus-of-Ota-Like Macules in Shanghai, China Bei-Qing Wang, Zheng-Yu Shen, Ye Fei, Hong Li, Jian-Hang.

Satisfaction With Activity and Participation and Its Relationships With Body Functions, Activities, or Environmental Factors in Stroke Patients Édouard.

Presentation transcript:

A Study of GWAS-Supported Variants of rs9943582 in a Chinese Han Population with Ischemic Stroke: No Associations with Disease Onset and Clinical Outcomes Hao Zhang, MD, Lingli Sun, MD, Huaiming Wang, MD, Huan Cai, MD, Guozhong Niu, MD, Yongjie Bai, MD, Yun Zhang, MD, Dong Yang, MD, Mengmeng Gu, MD, Pengfei Xu, MD, Xinying Fan, MD, PhD, Xinfeng Liu, MD, PhD, Gelin Xu, MD, PhD Journal of Stroke and Cerebrovascular Diseases Volume 26, Issue 10, Pages 2294-2299 (October 2017) DOI: 10.1016/j.jstrokecerebrovasdis.2017.05.013 Copyright © 2017 National Stroke Association Terms and Conditions

Figure 1 Correlation between variant rs9943582 and age at IS onset. (A) Box plot of age at IS onset for 3 different genotypes of rs9943582 (CC, CT, and TT). The boxes represent the interquartile range (25th to 75th percentile), and the horizontal line at the middle of every box stands for the median for each subgroup data. The whiskers extend to the 1.5 times of both sides of the total interquartile range. Outside dots indicate the values outside the whiskers. (B) Comparison of age at IS onset among different rs9943582 genotypes (CC, CT, and TT). Journal of Stroke and Cerebrovascular Diseases 2017 26, 2294-2299DOI: (10.1016/j.jstrokecerebrovasdis.2017.05.013) Copyright © 2017 National Stroke Association Terms and Conditions