October 20, 2016 Farrokh Alemi, PhD.

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Presentation transcript:

October 20, 2016 Farrokh Alemi, PhD. Identifying Sequence October 20, 2016 Farrokh Alemi, PhD.

Every Multivariate Analysis Makes Sequence Assumptions

Covariates Are Measured at Baseline

Treatment is after Baseline

Outcomes Are Last

Sequence of Cross-Sectional Study Covariates Treatment Outcome

Sequence of Diagnoses in a Cross-Sectional Study

Longitudinal Studies Indicate Timing

Different Variables for Same Event before or after Treatment

Definition of Variable Can Indicate Sequence Demographics Medical History

Sequence Can Be Discovered, But Is Often Ignored

Many Algorithms Same Conclusions

Install Package install.packages("bnlearn") library(bnlearn)

Read Data, Remove Unwanted Variables d=read.csv("simulatedbundleddata.csv") d=d[,-1] for(i in 1:ncol(d)){ d[,i]=as.factor(d[,i]) }

Download & Paste Blacklist Function Time 1 Time 2 Black list

Now Test Different Algorithms Same Answer ##For grow-shrink use l=gssequence(d) ##For incremental association use l=iambsequence(d) ##For semi-interleaved HITON use l=hitonsequence(d)

Sequence Is Fundamental