Ewing sarcoma/primitive neuroectodermal tumor of the kidney

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Ewing sarcoma/primitive neuroectodermal tumor of the kidney Maryam Abolhasani, Sareh Salarinejad, Mohammad Kazem Moslemi International Journal of Surgery Case Reports Volume 28, Pages 330-334 (January 2016) DOI: 10.1016/j.ijscr.2016.10.014 Copyright © 2016 The Author(s) Terms and Conditions

Fig. 1 Microscopic examination and IHC study of tumoral cells (×400). (A) H&E: Discohesive small round cells arranged as vague rosettes. (B) CD 99: Positive membranous staining in tumoral cells. (C) NSE: Positive cytoplasmic staining in tumoral cells. (D) CD 45: Negative in tumoral cells. (E) CD 56: Negative in tumoral cells. (F) CK 7: Positive cytoplasmic staining in surface urothelial cells and negative in tumoral cells. G- CK 20: Negative in surface urothelial cells and tumoral cells. H- Synaptophysin: Negative in tumoral cells. I- Chromogranin: Negative in tumoral cells. International Journal of Surgery Case Reports 2016 28, 330-334DOI: (10.1016/j.ijscr.2016.10.014) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 2 Nephrectomy specimen after neoadjuvant chemotherapy. Only a necrotic area was noted in lower pole which failed to prove any residue of tumoral cells in microscopic examination. International Journal of Surgery Case Reports 2016 28, 330-334DOI: (10.1016/j.ijscr.2016.10.014) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 3 CT scan of the third case revealing a large inhomogenous left renal mass occupying the left side of abdomen. International Journal of Surgery Case Reports 2016 28, 330-334DOI: (10.1016/j.ijscr.2016.10.014) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 4 Small round cells with high N/C ratio, rather round monotonous nuclei and scanty cytoplasm (×400). International Journal of Surgery Case Reports 2016 28, 330-334DOI: (10.1016/j.ijscr.2016.10.014) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 5 CD 99 was diffusely positive in tumoral cells (×20). International Journal of Surgery Case Reports 2016 28, 330-334DOI: (10.1016/j.ijscr.2016.10.014) Copyright © 2016 The Author(s) Terms and Conditions