Procedure for submission and approval of activities involving Genetically Modified Animals and Plants Complete GM Risk Assessment Form Submit to Administrator for GM and Biological Safety Considered by Local GM Safety Committee Project Approved Local Safety Representative Email form to CBS Manager Amendments required Revisions Required Issued by Administrator for GM and Biological Safety Project Approved by CBS Manager Email form to GM Chair Project Approved with green form issued by GM Chair Email form to the Administrator Revisions verified by College GMSO Email form to Local Safety Representative Principal Investigator addresses amendments Email form to College GMSO Approval issued to PrincipaI Investigator by Administrator for GM and Biological Safety Notifiable Non-notifiable CU2 form completed by Principal Investigator Submitted to GMSO with cheque payable to HSE (Current costs are given in Guidance Note 050) HSE notified by College GMSO HSE provides written consent (usually within 45 days) Work can start Work can start All GM protocols should be submitted to the Administrator for GM and Biological Safety