VEGF levels in CSF and serum in mild ALS patients

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VEGF levels in CSF and serum in mild ALS patients Gao Lina , Zhou Shaodan , Cai Haowei , Gong Zhongying , Zang Dawei Journal of the Neurological Sciences Volume 346, Issue 1, Pages 216-220 (November 2014) DOI: 10.1016/j.jns.2014.08.031 Copyright © 2014 Elsevier B.V. Terms and Conditions

Fig. 1 VEGF levels of ALS patients and controls. Levels of VEGF in the CSF (A) and serum (B) of ALS patients and control subjects. * shows that the VEGF levels in CSF and serum are significantly higher in ALS patients than those in control subjects (P=0.009 and P<0.001, respectively). Journal of the Neurological Sciences 2014 346, 216-220DOI: (10.1016/j.jns.2014.08.031) Copyright © 2014 Elsevier B.V. Terms and Conditions

Fig. 2 Correlations between CSF (A) and serum (B) VEGF levels of ALS patients and their duration. A, B: The correlations between CSF and serum VEGF levels with the duration of ALS patients are positive and significant (P=0.0432, P=0.0219, respectively). Journal of the Neurological Sciences 2014 346, 216-220DOI: (10.1016/j.jns.2014.08.031) Copyright © 2014 Elsevier B.V. Terms and Conditions

Fig. 3 CSF and serum VEGF levels of ALS patients in duration (0–12months) subgroup and duration (12+months) subgroup. * shows that the VEGF levels in CSF (A) and serum (B) of ALS patients are significantly higher in duration (12+months) subgroup than those in duration (0–12months) subgroup (P=0.040 and P=0.039, respectively). Journal of the Neurological Sciences 2014 346, 216-220DOI: (10.1016/j.jns.2014.08.031) Copyright © 2014 Elsevier B.V. Terms and Conditions

Fig. 4 Correlations between CSF (A) and serum (B) VEGF levels of ALS patients and their disease progression rate (DPR). A, B: The correlations between CSF and serum VEGF levels with the disease progression rate (DPR) of ALS patients are negative and significant (P=0.0482, P=0.0353, respectively). Journal of the Neurological Sciences 2014 346, 216-220DOI: (10.1016/j.jns.2014.08.031) Copyright © 2014 Elsevier B.V. Terms and Conditions

Fig. 5 CSF and serum VEGF levels of ALS patients in DPR (0–1) subgroup and DPR (1+) subgroup. * shows that the VEGF levels in serum (B) of ALS patients are significantly higher in DPR (0–1) subgroup than those in DPR (1+) subgroup (P=0.025). Journal of the Neurological Sciences 2014 346, 216-220DOI: (10.1016/j.jns.2014.08.031) Copyright © 2014 Elsevier B.V. Terms and Conditions