Opioid Concentrations in Oral Fluid and Plasma in Cancer Patients With Pain Tarja Heiskanen, MD, PhD, Kaarina Langel, MSc, Teemu Gunnar, BSc, MSc, Pirjo.

Slides:

Advertisements

Similar presentations

Impact of a Clinical Pharmacist-Led Guidance Team on Cancer Pain Therapy in China: A Prospective Multicenter Cohort Study Jian Chen, PhD, Xiao-yang Lu,

Advertisements

Palliative Sedation at Home for Terminally Ill Children With Cancer

YouTube as a Tool for Pain Management With Informal Caregivers of Cancer Patients: A Systematic Review Elaine Wittenberg-Lyles, PhD, Debra Parker Oliver,

Anxiety After Diagnosis Predicts Lung Cancer–Specific and Overall Survival in Patients With Stage III Non–Small Cell Lung Cancer: A Population-Based Cohort.

Mindfulness-Oriented Recovery Enhancement Ameliorates the Impact of Pain on Self- Reported Psychological and Physical Function Among Opioid-Using Chronic.

Constanze Rémi, MSc, Jan Rémi, MD, Claudia Bausewein, PhD, MD, MSc

An Educational Intervention to Reduce Pain and Improve Pain Management for Malawian People Living With HIV/AIDS and Their Family Carers: A Randomized.

The Burden of Polypharmacy in Patients Near the End of Life

Arjun Poudel, PhD, Patsy Yates, PhD, Debra Rowett, BPharm, Lisa M

Impact of a Clinical Pharmacist-Led Guidance Team on Cancer Pain Therapy in China: A Prospective Multicenter Cohort Study Jian Chen, PhD, Xiao-yang Lu,

Accuracy of a Diagnostic Algorithm to Diagnose Breakthrough Cancer Pain as Compared With Clinical Assessment Katherine Webber, MBBS, MSc, PhD, Andrew.

Impact of Prophylactic Fentanyl Pectin Nasal Spray on Exercise-Induced Episodic Dyspnea in Cancer Patients: A Double-Blind, Randomized Controlled Trial

Petter Wilberg, DDS, Marianne J

James H. Flory, MD, MSCE, Alison C. Wiesenthal, MD, Howard T

Building Resilience for Palliative Care Clinicians: An Approach to Burnout Prevention Based on Individual Skills and Workplace Factors Anthony L. Back,

Cross-Sectional Pilot Study to Monitor the Availability, Dispensed Prices, and Affordability of Opioids Around the Globe Liliana De Lima, MHA, Tania.

Gregory P. Samsa, PhD, Steven Wolf, MB, Thomas W

Vincent Maida, MD, MSc, BSc, Jason Corban, MD, CM, Hon BSc

Associations Between Objectively Measured Physical Activity and Quality of Life in Cancer Patients With Brain Metastases Sonya S. Lowe, MD, MSc, Brita.

Nordic Walking as an Exercise Intervention to Reduce Pain in Women With Aromatase Inhibitor–Associated Arthralgia: A Feasibility Study Jo Fields, DClinP,

Andrew Davies, FRCP, Katherine Webber, PhD

Fentanyl Pectin Nasal Spray Versus Oral Morphine in Doses Proportional to the Basal Opioid Regimen for the Management of Breakthrough Cancer Pain: A Comparative.

Isaac M. Bromberg, MD Journal of Pain and Symptom Management

Reliability and Validity of the Korean Memorial Symptom Assessment Scale—Short Form in Gynecological Cancer Patients Ju-Hee Nho, PhD, RN, Sung Reul Kim,

Palliative Care in Romania

Developing a Costing Framework for Palliative Care Services

Resource Use and Health Care Costs of COPD Patients at the End of Life: A Systematic Review Kristof Faes, MSc, Veerle De Frène, PhD, Joachim Cohen, PhD,

Jacob N. Hunnicutt, MPH, Jennifer Tjia, MD, MS, Kate L. Lapane, PhD

A Systematic Review of Training in Symptom Management in Palliative Care Within Postgraduate Medical Curriculums Pamela Turrillas, MD, MSc, Maria Joao.

Comparative Analysis of Specialization in Palliative Medicine Processes Within the World Health Organization European Region Carlos Centeno, PhD, Deborah.

The Opioid Rotation Ratio From Transdermal Fentanyl to “Strong” Opioids in Patients With Cancer Pain Akhila Reddy, MD, Sriram Yennurajalingam, MD, MS,

Mindfulness-Oriented Recovery Enhancement Ameliorates the Impact of Pain on Self- Reported Psychological and Physical Function Among Opioid-Using Chronic.

Nancy E. Avis, PhD, Beverly Levine, PhD, Sarah A

Changes in Nurses' Knowledge, Difficulties, and Self-reported Practices Toward Palliative Care for Cancer Patients in Japan: An Analysis of Two Nationwide.

The Relationship Between Fatigue and Depression in Adults With End-Stage Renal Disease on Chronic In-Hospital Hemodialysis: A Scoping Review Janine F.

Palliative Sedation at Home for Terminally Ill Children With Cancer

Documentation Quality of Inpatient Code Status Discussions

The Nexus Between the Documentation of End-of-Life Wishes and Awareness of Dying: A Model for Research, Education and Care Deborah P. Waldrop, PhD, MSW,

How Do Follow-Up Care Instructions and Treatment Summaries Relate to Cancer Survivors' Cancer-Related Pain? Jennifer M. Jabson, PhD, MPH, Deborah J.

Katherine Webber, MBBS, MSc, PhD, Andrew N. Davies, FRCP, Martin R

Opioid Concentrations in Oral Fluid and Plasma in Cancer Patients With Pain Tarja Heiskanen, MD, PhD, Kaarina Langel, MSc, Teemu Gunnar, BSc, MSc, Pirjo.

Psychometric Properties of the Fatigue Questionnaire EORTC QLQ-FA12 in a Sample of Female Cancer Patients Sophie Kecke, Jochen Ernst, PhD, Jens Einenkel,

Factors Related to Adherence to Opioids in Black Patients With Cancer Pain Katherine A. Yeager, PhD, RN, FAAN, Bryan Williams, PhD, Jinbing Bai, PhD,

Variations in Vital Signs in the Last Days of Life in Patients With Advanced Cancer Sebastian Bruera, Gary Chisholm, MS, Renata Dos Santos, MD, Camila.

Author's Response Journal of Pain and Symptom Management

Locked-In Syndrome: Case Report and Discussion of Decisional Capacity

Antonio T. Fernando, MD, Nathan S. Consedine, PhD

Integrated Onco-Palliative Care Associated With Prolonged Survival Compared to Standard Care for Patients With Advanced Lung Cancer: A Retrospective Review

What Aspects of Quality of Life Are Important From Palliative Care Patients' Perspectives? A Systematic Review of Qualitative Research Nicola McCaffrey,

Prevalence of Neuropathic Pain in Cancer Patients: Pooled Estimates From a Systematic Review of Published Literature and Results From a Survey Conducted.

U.S. Hospice Benefits Journal of Pain and Symptom Management

Jonathan M. Marron, MD, MPH, Emma Jones, MD, Joanne Wolfe, MD, MPH

Which Treatment Is Better

William Shomali, MD Journal of Pain and Symptom Management

Pain and Policy Studies Group: Two Decades of Working to Address Regulatory Barriers to Improve Opioid Availability and Accessibility Around the World

Validation of the Modified Glasgow Prognostic Score in Advanced Cancer Patients Receiving Palliative Care Naitielle de Paula Pantano, RN, Bianca Sakamoto.

Karla T. Washington, PhD, Christopher R. Rakes, PhD

Missed Opportunities: A Mixed-Methods Analysis of CAM Discussions and Practices in the Management of Pain in Oncology Aaron L. Leppin, MD, MSc, Cara.

Psychoeducational Intervention for Symptom Management of Fatigue, Pain, and Sleep Disturbance Cluster Among Cancer Patients: A Pilot Quasi-Experimental.

Prognostic Tools in Patients With Advanced Cancer: A Systematic Review

Logan H. Ramsey, BS Journal of Pain and Symptom Management

Bruce L. Arnold, PhD, Linda S. Lloyd, DrPH, Charles F

Population-Based Quality Indicators for Palliative Care Programs for Cancer Patients in Japan: A Delphi Study Yoko Nakazawa, RN, MSH, Masahi Kato, MD,

Katherine Webber, MBBS, Andrew N

Lisa C. Lindley, PhD, RN, Jennifer W. Mack, MD, MPH, Donald J

Is It the Difference a Day Makes

Trend in and Correlates of Undergoing Radiotherapy in Taiwanese Cancer Patients' Last Month of Life Yen-Ni Hung, PhD, Skye Hung-Chun Cheng, MD, Tsang-Wu.

Associations Between Physical Activity and Quality of Life in Cancer Patients Receiving Palliative Care: A Pilot Survey Sonya S. Lowe, MD, MSc, Sharon.

Patient-Controlled Analgesia for Children at Home

A Quantitative Study of Triggered Palliative Care Consultation for Hospitalized Patients With Advanced Cancer Gabrielle B. Rocque, MD, Toby C. Campbell,

Presentation transcript:

Opioid Concentrations in Oral Fluid and Plasma in Cancer Patients With Pain Tarja Heiskanen, MD, PhD, Kaarina Langel, MSc, Teemu Gunnar, BSc, MSc, Pirjo Lillsunde, PhD, Eija A. Kalso, MD, DMedSci Journal of Pain and Symptom Management Volume 50, Issue 4, Pages 524-532 (October 2015) DOI: 10.1016/j.jpainsymman.2014.09.004 Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 1 Flowchart. OF = oral fluid. Journal of Pain and Symptom Management 2015 50, 524-532DOI: (10.1016/j.jpainsymman.2014.09.004) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 2 Variations of opioid doses and plasma opioid concentrations. *Denotes the furthest outlying single measurement values in relation to the mean value of 5 measurements in a patient. Journal of Pain and Symptom Management 2015 50, 524-532DOI: (10.1016/j.jpainsymman.2014.09.004) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 3 Correlations of oral fluid and plasma opioid concentrations. Journal of Pain and Symptom Management 2015 50, 524-532DOI: (10.1016/j.jpainsymman.2014.09.004) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 4 Inter- and intrapatient variation in oral fluid and plasma opioid concentration ratios in patients (N = 29) who gave all five oral fluid and plasma samples over different time points. OF/P = oral fluid/plasma. *Denotes the furthest outlying single measurement values in relation to the mean value of 5 measurements in a patient. Journal of Pain and Symptom Management 2015 50, 524-532DOI: (10.1016/j.jpainsymman.2014.09.004) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions