M. Gallidabino, C. Weyermann, R. Marquis

Slides:

Advertisements

Similar presentations

Illa Tea, Ingrid Antheaume, Ben-Li Zhang

Advertisements

The importance of Guthrie cards and other medical samples for the direct matching of disaster victims using DNA profiling D. Hartman, L. Benton, L. Morenos,

In situ silver nanoparticles synthesis in agarose film supported on filter paper and its application as highly efficient SERS test stripes Ali Raza,

Validation of a headspace solid-phase microextraction–GC–MS/MS for the determination of ethyl glucuronide in hair according to forensic guidelines Ronald.

Analysis of Indian blue ballpoint pen inks tagged with rare-earth thenoyltrifluoroacetonates by inductively coupled plasma–mass spectrometry and instrumental.

Flávia de Souza Lins Borba, Ricardo Saldanha Honorato, Anna de Juan

The ideal subject distance for passport pictures

Intra-individual gait pattern variability in specific situations: Implications for forensic gait analysis Oliver Ludwig, Steffen Dillinger, Franz Marschall

Two fatal intoxication cases with imidacloprid: LC/MS analysis

High-performance combination method of electric network frequency and phase for audio forgery detection in battery-powered devices Maryam Savari, Ainuddin.

Chemical characterization of synthetic cannabinoids by electrospray ionization FT-ICR mass spectrometry Jade B. Kill, Izabela F. Oliveira, Lilian V.

A modified Raman multidimensional spectroscopic signature of blood to account for the effect of laser power Gregory McLaughlin, Igor K. Lednev Forensic.

Piotr Adamowicz, Dariusz Zuba, Karolina Sekuła

Gregory McLaughlin, Vitali Sikirzhytski, Igor K. Lednev

A snapshot on NPS in Italy: Distribution of drugs in seized materials analysed in an Italian forensic laboratory in the period 2013–2015 Sara Odoardi,

A snapshot on NPS in Italy: Distribution of drugs in seized materials analysed in an Italian forensic laboratory in the period 2013–2015 Sara Odoardi,

Determination of ketamine and norketamine in hair by micropulverized extraction and liquid chromatography–high resolution mass spectrometry Donata Favretto,

Simultaneous determination of mushroom toxins α-amanitin, β-amanitin and muscarine in human urine by solid-phase extraction and ultra-high-performance.

Detection of 3-methylmethcathinone and its metabolites 3-methylephedrine and 3- methylnorephedrine in pubic hair samples by liquid chromatography–high.

Purple discoloration of the colon found during autopsy: Identification of betanin, its aglycone and metabolites by liquid chromatography–high-resolution.

Direct analysis in real time high resolution mass spectrometry as a tool for rapid characterization of mind-altering plant materials and revelation of.

Effective injection in pulsed splitless mode for impurity profiling of methamphetamine crystal by GC or GC/MS Tetsuro Sasaki, Yukiko Makino Forensic.

The homogeneity testing of EtG in hair reference materials: A high-throughput procedure using GC–NCI–MS Bettina Mönch, Roland Becker, Christian Jung,

Yun Sik Nam, Il Keun Kwon, Yeonhee Lee, Kang-Bong Lee

Forensic Science International

A comparative study of ballpoint ink ageing parameters using GC/MS

Development of a GC–MS method for methamphetamine detection in Calliphora vomitoria L. (Diptera: Calliphoridae) Paola A. Magni, Tommaso Pacini, Marco.

Profiling counterfeit Cialis, Viagra and analogs by UPLC–MS

Fatal intoxication due to ackee (Blighia sapida) in Suriname and French Guyana. GC– MS detection and quantification of hypoglycin-A Yvan Gaillard, Jérémie.

Rapid screening for detection and differentiation of detergent powder adulteration in infant milk formula by LC–MS Manjun Tay, Guihua Fang, Poh Ling.

Regioisomeric bromodimethoxy benzyl piperazines related to the designer substance 4- bromo-2,5-dimethoxybenzylpiperazine: GC–MS and FTIR analysis Karim.

New perspectives in the use of ink evidence in forensic science: Part I. Development of a quality assurance process for forensic ink analysis by HPTLC

Gowri Vijay Reesu, Nathan Lee Brown Forensic Science International

Ballistic skin simulant

Identification, extraction and quantification of the synthetic cannabinoid JWH-018 from commercially available herbal marijuana alternatives Sage J.B.

LC–MS method development and comparison of sampling materials for the analysis of organic gunshot residues Anne-Laure Gassner, Céline Weyermann Forensic.

Cuiling Zhang, Joost van de Weijer, Jingxu Cui

Application of CdSe nanoparticle suspension for developing latent fingermarks on the sticky side of adhesives Yuan Feng Wang, Rui Qin Yang, Yan Ji Wang,

Elemental analysis of glass by laser ablation inductively coupled plasma optical emission spectrometry (LA-ICP-OES) Emily R. Schenk, José R. Almirall

The discrimination potential of diffuse-reflectance ultraviolet–visible–near infrared spectrophotometry for the forensic analysis of paper Valerio Causin,

The discrimination potential of diffuse-reflectance ultraviolet–visible–near infrared spectrophotometry for the forensic analysis of paper Valerio Causin,

Instability of calcium channel antagonists during sample preparation for LC–MS–MS analysis of serum samples Ana B. Baranda, Rosa M. Alonso, Rosa M. Jiménez,

The discrimination of automotive clear coats by pyrolysis-gas chromatography/mass spectrometry and comparison of samples by a chromatogram library software

Forensic Science International

New perspectives in the use of ink evidence in forensic science

The characterisation of two halogenated cathinone analogues: 3,5- Difluoromethcathinone and 3,5-dichloromethcathinone Sean Davis, Karen Rands-Trevor,

Magdalena Ezcurra Forensic Science International

Fluorescence imaging of petroleum accelerants by time-resolved spectroscopy with a pulsed Nd-YAG laser Naoki Saitoh, Shigeki Takeuchi Forensic Science.

Functionalised silicon oxide nanoparticles for fingermark detection

Forensic analysis of biodiesel

Quantitative bloodstain analysis: Differentiation of contact transfer patterns versus spatter patterns on fabric via microscopic inspection Yuen Cho,

Identification of gunshots to the head by detection of RNA in backspatter primarily expressed in brain tissue Constantin Lux, Christian Schyma, Burkhard.

Passport examination by a confocal-type laser profile microscope

Evidence of mephedrone chronic abuse through hair analysis using GC/MS

Evidence of mephedrone chronic abuse through hair analysis using GC/MS

Janina Zięba-Palus, Marcin Kunicki Forensic Science International

Combination of prostate-specific antigen detection and micro-Raman spectroscopy for confirmatory semen detection Ilan Feine, Ron Gafny, Iddo Pinkas

Marcin Milanowicz, Krzysztof Kędzior Forensic Science International

A. Verzeletti, V. Cortellini, S. Cisana, S. Pretto, N. Cerri, F

DTT quenches the passive reference signal in real-time PCR

Probabilistic modelling for DNA mixture analysis

Mitochondrial DNA typing with the matrix-assisted laser desorption/ionization time-of- flight mass spectrometry Y.P. Hou, X.M. Sun, J. Yan, J. Wu, Y.B.

Combining DNA evidence for greater match information

Oskar Hansson, Peter Gill

A. Verzeletti, V. Cortellini, S. Cisana, S. Pretto, N. Cerri, F

A review of low template STR analysis in casework using the DNA SenCE post-PCR purification technique T. Gross, J. Thomson, S. Kutranov Forensic Science.

Volume 95, Issue 3, Pages (August 2008)

Development of a 24-plex Y chromosomal STR loci typing system

Statistical aspects of familial searching

Steffen L. Lauritzen, Anjali Mazumder

Presentation transcript:

Differentiation of blue ballpoint pen inks by positive and negative mode LDI-MS M. Gallidabino, C. Weyermann, R. Marquis Forensic Science International Volume 204, Issue 1, Pages 169-178 (January 2011) DOI: 10.1016/j.forsciint.2010.05.027 Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Examples of irradiance effects on resolutions (m/Δm) of selected peaks. Peak resolution is decreasing as a function of nominal laser irradiance in LDI-MS positive and negative modes, represented here by molecular ions of dyes BV3 and SB38, respectively. The resolution was observed to decrease importantly when using laser irradiance values over 72 for positive and over 80 for negative mode, respectively. Right dotted and left dash-dotted lines represent nominal irradiance values chosen to acquire ballpoint inks spectra in positive and negative modes, respectively. Forensic Science International 2011 204, 169-178DOI: (10.1016/j.forsciint.2010.05.027) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Representation of irradiance effect on spectrum maximal intensity. Signal maximal intensity (mV) increases in function of nominal laser irradiance in LDI-MS positive and negative modes. Right dotted and left dash-dotted lines represent nominal irradiance values chosen to acquire ballpoint inks spectra in positive and negative modes, respectively. Forensic Science International 2011 204, 169-178DOI: (10.1016/j.forsciint.2010.05.027) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Examples of irradiance effects on RPA values. (a) Shows effects on BV3 in positive mode: RPA372 (BV3) decreased as a function of nominal laser irradiance, while RPA358 (BV3 – Me) and RPA344 (BV3 – 2Me) increased. This effect is particularly marked over a laser irradiance value of 64. (b) Shows similar effects on SB38 in negative mode: RPA815 (SB38+SO3H) decreased as a function of nominal laser irradiance, while RPA735 (SB38) and RPA895 (SB38+2SO3H) increased. This effect is particularly marked over a laser irradiance value of 84. Dotted line in (a) and dash-dotted line in (b) represent nominal irradiance values chosen to acquire ballpoint inks spectra in positive and negative modes, respectively. Forensic Science International 2011 204, 169-178DOI: (10.1016/j.forsciint.2010.05.027) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 Effects on signal resolution of SB38 peaks in LDI-MS negative mode when the nominal laser irradiance was increased from 80 (a) to 92 (b). In negative spectra, signal corresponding to SB38 is a mixture of its radical anion [CuPc(SO3H)2]− and the respective anionic species CuPc(SO3H)(SO3−). The summed isotopic pattern between this species is visible when laser irradiance is suitable (a). However, the isotopic information was lost when the laser irradiance was set too high and as a consequence only the average mass could then be determined (b). Forensic Science International 2011 204, 169-178DOI: (10.1016/j.forsciint.2010.05.027) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 5 Structure of copper phthalocyanines (CuPc) derivatives identified in blue ballpoint inks together with m/z values of corresponding ions. The difference between these molecules lies in the number of sulfonic acid functional groups added to the basic structure. Forensic Science International 2011 204, 169-178DOI: (10.1016/j.forsciint.2010.05.027) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 6 Structure of two dyes detected in inks using LDI-MS negative mode, together with theoretical m/z values of corresponding negative ions. Forensic Science International 2011 204, 169-178DOI: (10.1016/j.forsciint.2010.05.027) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 7 LDI positive (a) and negative (b) mass spectra of ballpoint pen #2. In positive mass spectrum, only the dye BV3 and its fragmentation products were identified (m/z=372.2, 358.2 and 344.2). On the other hand, in negative mass spectrum numerous dyes were present: AB9 (m/z=170.2 and 185.2), AB92 (m/z=313.5 and 628.0), SB38 (m/z=735.0) and its mono-sulfonic acid derivative (m/z=815.0). (c) Shows the HPTLC plate of the same ink. The dye SB38 (spot 1), AB9 (two spots 2), AB92 (spot 3) and BV3 (three spots 5) were identified by comparison of the retention times and colors with reference substances. While the retention time of spot 4 did correspond to the reference substance BG4, the identification could not be confirmed by LDI-MS results. Forensic Science International 2011 204, 169-178DOI: (10.1016/j.forsciint.2010.05.027) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions