Volume 94, Issue 3, Pages (May 2011)

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Volume 94, Issue 3, Pages 206-212 (May 2011) Increased indoleamine 2,3-dioxygenase (IDO) activity in idiopathic generalized epilepsy Suvi Liimatainen, Kai Lehtimäki, Annika Raitala, Maria Peltola, Simo S. Oja, Jukka Peltola, Mikko A. Hurme Epilepsy Research Volume 94, Issue 3, Pages 206-212 (May 2011) DOI: 10.1016/j.eplepsyres.2011.02.003 Copyright © 2011 Elsevier B.V. Terms and Conditions

Figure 1 Kyn/trp ratio in control subjects and in patients with different epilepsy syndromes. SEM, standard error of mean; TLE (HS−), temporal lobe epilepsy but no hippocampal sclerosis; TLE (HS+), temporal lobe epilepsy with hippocampal sclerosis; extra-TLE, extra-temporal lobe epilepsy; multifocal, multifocal epilepsy; IGE, unclassified idiopathic epilepsy; JME, juvenile myoclonic epilepsy. *IDO activity was increased in the patients with JME (p=0.04) and unclassified IGE (p=0.05) compared to the control subjects. Epilepsy Research 2011 94, 206-212DOI: (10.1016/j.eplepsyres.2011.02.003) Copyright © 2011 Elsevier B.V. Terms and Conditions

Figure 2 Number of patients with last month seizure freedom according to epilepsy syndromes. TLE (HS−), temporal lobe epilepsy but no hippocampal sclerosis; TLE (HS+), temporal lobe epilepsy with hippocampal sclerosis; extra-TLE, extra-temporal lobe epilepsy; multifocal, multifocal epilepsy; IGE, unclassified idiopathic epilepsy; JME, juvenile myoclonic epilepsy. Epilepsy Research 2011 94, 206-212DOI: (10.1016/j.eplepsyres.2011.02.003) Copyright © 2011 Elsevier B.V. Terms and Conditions

Figure 3 Kyn/trp ratio according to etiology of epilepsy. SEM, standard error of mean; **p=0.003 compared to the control subjects. Epilepsy Research 2011 94, 206-212DOI: (10.1016/j.eplepsyres.2011.02.003) Copyright © 2011 Elsevier B.V. Terms and Conditions