Increased plasma UCH-L1 after aneurysmal subarachnoid hemorrhage is associated with unfavorable neurological outcome  Heikki Kiiski, Jyrki Tenhunen, Marika Ala-Peijari, Heini Huhtala, Mari Hämäläinen, Jaakko Långsjö, Eeva Moilanen, Susanna Narkilahti, Juha Öhman, Jukka Peltola  Journal of the Neurological Sciences  Volume 361, Pages 144-149 (February 2016) DOI: 10.1016/j.jns.2015.12.046 Copyright © 2015 Elsevier B.V. Terms and Conditions

Fig. 1 UCH-L1 levels for all patients and all time-intervals. Values are grouped by a favorable and an unfavorable neurological outcome. Dots represent individual patient values. Line represents group median. Outliers are included in the medians but not shown in the graph. Journal of the Neurological Sciences 2016 361, 144-149DOI: (10.1016/j.jns.2015.12.046) Copyright © 2015 Elsevier B.V. Terms and Conditions

Fig. 2 UCH-L1 levels during the first 24h after aSAH between patients (n=47) with a favorable and an unfavorable neurological outcome. Outliers are included to statistical analysis but not shown in the graph (a). UCH-L1 levels at the end of five-day follow-up between patients (n=22) with a favorable and an unfavorable neurological outcome (b). Journal of the Neurological Sciences 2016 361, 144-149DOI: (10.1016/j.jns.2015.12.046) Copyright © 2015 Elsevier B.V. Terms and Conditions

Fig. 3 UCH-L1 levels for patients with a follow-up for up to five days (n=22). Dots represent individual patient values. Values are grouped by favorable and non-favorable neurological outcome. Linear regression shows significant elevation of UCH-L1 concentration during follow-up in patients with non-favorable (p=0.026, beta=0.416) outcome but concentration remains at base level in patients with favorable outcome (p=0.890, beta=−0.034). Journal of the Neurological Sciences 2016 361, 144-149DOI: (10.1016/j.jns.2015.12.046) Copyright © 2015 Elsevier B.V. Terms and Conditions