Pediatric vascular anomalies

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Presentation transcript:

Pediatric vascular anomalies Dr Sami Billal MSc,MD

There are two major groups of vascular anomalies 1- Vascular tumors – neoplasms of a particular type of blood vessel or other vascular tissue Tumors will proliferate and some never stop without therapy 2- Vascular malformations – A lesion of abnormal blood vessels that does not have rapid proliferation Malformations are static or very slow growing

Infantile hemangioma (IH) Pyogenic granuloma Congenital hemangioma Vascular tumors Infantile hemangioma (IH) Pyogenic granuloma Congenital hemangioma Tufted angioma Kaposiform hemangioendothelioma Angiosarcoma

Vascular malformations Capillary malformations (CM) Cutaneous or mucosal CM (“Port-wine” stain) Nevus simplex (“salmon patch”) Cutis marmorata telangiectatica congenita (CMTC) Lymphatic malformations Venous malformations Arterial malformations Arteriovenous malformations Combined malformations

Infantile hemangioma (IH) Infantile hemangiomas (IH) are common benign vascular tumors of infancy occurring in about 4% of infants At birth, a premonitory mark may be present such as a bruise-like patch, area of vasoconstriction/pallor or telangiectasias

Risk factors for developing IH Low birth weight Female gender Twin gestation Fair skin

IH at 2 weeks old

Infantile hemangiomas proliferate during the first 2-3 months of life Growth usually stabilizes around 4-6 months, followed by involution over years Larger, deeper IH grow for longer and involutes more slowly. Based on these growth characteristics, IH requiring intervention should be referred for treatment before 3 months of age

Types of heamangiomas Deep large with a bluish color Superficial bright red and minimally elevated Deep large with a bluish color Mixed have both components

Hemangiomas: clinical appearance Hemangiomas may occur anywhere on the body They may be localized or segmental/regional in distribution

Complications include: Ulceration Visual Impairment Airway involvement Multifocal presentation Aesthetic complications Complex Associations

Infantile Hemangiomas: Management Systemic Therapies Oral propranolol Systemic corticosteroids Immunosuppressive or anti-neoplastic* therapies (Interferon, Vincristine)

Topical corticosteroids Topical beta blockers Local Therapies Topical corticosteroids Topical beta blockers Intralesional corticosteroids Pulsed dye laser for ulceration or residual lesions

Clinical Case HPI: This is an 8 day old baby boy who presents for evaluation of a large, pink mark on his forehead present at birth. His parents are concerned by the size and location of the birthmark. PMH: Born full term to healthy mother, no pregnancy or labor complications, received all vaccinations

Nevus simplex Nevus simplex (salmon patch) is a type of faint, transient capillary malformation Present in 30-40% of newborns, it is the most common pediatric vascular lesion Flat, pink to bright red patches typically on the midline forehead, scalp, upper eyelids, posterior neck and back. Children often have multiple The redness will become accentuated during episodes of increased internal pressure (crying, straining with defecation or physical exertion)

Management In general, there are no findings associated with nevus simplex that require workup or evaluation 95% of facial lesions fade within 1-2 years making treatment unnecessary

Clinical Case HPI: This is a 6 month old baby who presents with a lesion on her face that has been present since birth and has been growing in size. The lesion is not itchy or painful. PMH: Born at 38 weeks to healthy mother via C-section, no pregnancy or labor complications. No medical conditions.

Dull red patch on the face involving the upper eyelid, forehead, temple and scalp

Port-wine stain Capillary malformation present at birth Present as pink to dark red patches that are often unilateral with midline cutoff Can be found on any part of the body Tend to darken and thicken slowly over years May develop vascular papules and significant skin hypertrophy over many years

Port-wine stain

Management of Port-wine stain options include Conservative management – no treatment or use of cosmetics to conceal the lesions Pulse dye laser (PDL) – causes intravascular coagulation in abnormal vasculature without damaging surrounding structures