Volume 83, Issue 2, Pages 197-201 (February 2012) Serum matrix metalloproteinases in patients resuscitated from cardiac arrest. The association with therapeutic hypothermia Johanna Hästbacka, Marjaana Tiainen, Marja Hynninen, Elina Kolho, Taina Tervahartiala, Timo Sorsa, Anneli Lauhio, Ville Pettilä Resuscitation Volume 83, Issue 2, Pages 197-201 (February 2012) DOI: 10.1016/j.resuscitation.2011.07.036 Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions
Fig. 1 (a–d) Matrix metalloproteinase-7 (MMP-7) (a), -8 (b), -9 (c) and tissue inhibitor of metalloproteinases-1 (TIMP-1) (d) – levels in non-hypothermia (N=21) and hypothermia (N=30) treated patients at 24h and 48h from ROSC (restoration of spontaneous circulation). All hypothermia-treated were hypothermic at 24h and rewarmed at 48h. (e) Change in MMP-9 (delta MMP-9) and TIMP-1 (delta TIMP-1) levels in hypothermia- and non-hypothermia treated patients between 24h and 48h. Significance is considered at level p<0.01. Resuscitation 2012 83, 197-201DOI: (10.1016/j.resuscitation.2011.07.036) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions