Functional Capacity and Muscular Abnormalities in Subclinical Hypothyroidism Vaneska S. Reuters, MD, PhD, Patrícia de Fátima S. Teixeira, MD, PhD, Patrícia S. Vigário, MD, Cloyra P. Almeida, MD, PhD, Alexandre Buescu, MD, PhD, Márcia M. Ferreira, MD, Mario Vaisman, MD, PhD The American Journal of the Medical Sciences Volume 338, Issue 4, Pages 259-263 (October 2009) DOI: 10.1097/MAJ.0b013e3181af7c7c Copyright © 2009 Southern Society for Clinical Investigation Terms and Conditions
Figure 1 Prevalence of neuromuscular symptoms (patients versus controls). (A) Data from all participants: there was a greater prevalence of cramps, myalgia, and weakness in subclinical hypothyroidism in comparison to controls. (B) Data excluding smokers from analyses did not show modifications in results. *Statistical significance (P<0.05); #borderline significance (P ≥ 0.05 and ≤0.09). The American Journal of the Medical Sciences 2009 338, 259-263DOI: (10.1097/MAJ.0b013e3181af7c7c) Copyright © 2009 Southern Society for Clinical Investigation Terms and Conditions
Figure 2 Prevalence of participants with altered manual muscular test and abnormal quadriceps and inspiratory strength. (A) Data from all participants: the frequency of altered MMT was significantly higher in subclinical hypothyroidism when compared with controls; (B) Data excluding smokers did not alter the results. MMT, manual muscle testing; QS, quadriceps strength; IS, inspiratory strength. *Statistical significance (P<0.05). The American Journal of the Medical Sciences 2009 338, 259-263DOI: (10.1097/MAJ.0b013e3181af7c7c) Copyright © 2009 Southern Society for Clinical Investigation Terms and Conditions