American Heart Journal Ten-year clinical outcomes after sirolimus-eluting stent implantation: Impact of an in- stent restenosis target lesion  Katsuya Miura, MD, Kazushige Kadota, MD, PhD, Seiji Habara, MD, Hiroshi Miyawaki, MD, Takenobu Shimada, MD, Masanobu Ohya, MD, Hidewo Amano, MD, Yu Izawa, MD, Yusuke Hyodo, MD, Suguru Otsuru, MD, Daiji Hasegawa, MD, Takeshi Tada, MD, PhD, Hiroyuki Tanaka, MD, Yasushi Fuku, MD, Tsuyoshi Goto, MD, Kazuaki Mitsudo, MD  American Heart Journal  Volume 175, Pages 47-55 (May 2016) DOI: 10.1016/j.ahj.2016.02.005 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 Kaplan-Meier curves of all-cause death, cardiac death, MI, and definite ST through 10 years. Cumulative incidences of all-cause death (red), cardiac death (blue), MI (green), and definite ST (orange) through 10 years. American Heart Journal 2016 175, 47-55DOI: (10.1016/j.ahj.2016.02.005) Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 2 Kaplan-Meier curves of any coronary revascularization, TVR, TLR, and clinically driven TLR through 10 years. Cumulative incidences of any coronary revascularization (red), TVR (blue), TLR (green), and clinically driven TLR (orange) through 10 years. American Heart Journal 2016 175, 47-55DOI: (10.1016/j.ahj.2016.02.005) Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 3 Kaplan-Meier curves of TLR for patients with ISR lesion compared with those with de novo lesion. A, Cumulative incidences of TLR through 10 years: de novo lesion versus ISR lesion. B, Cumulative incidences of TLR within and beyond 5 years: de novo lesion versus ISR lesion. American Heart Journal 2016 175, 47-55DOI: (10.1016/j.ahj.2016.02.005) Copyright © 2016 Elsevier Inc. Terms and Conditions