Is serum Klotho protective against atherosclerosis in patients with type 1 diabetes mellitus? Nursen Keles, Burcu Dogan, Macit Kalcik, Mustafa Caliskan,

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Is serum Klotho protective against atherosclerosis in patients with type 1 diabetes mellitus? Nursen Keles, Burcu Dogan, Macit Kalcik, Mustafa Caliskan, Necibe Nur Keles, Feyza Aksu, Mustafa Bulut, Osman Kostek, Banu Isbilen, Yusuf Yilmaz, Aytekin Oguz Journal of Diabetes and Its Complications Volume 30, Issue 1, Pages 126-132 (January 2016) DOI: 10.1016/j.jdiacomp.2015.09.013 Copyright © 2016 Elsevier Inc. Terms and Conditions

Fig. 1 Comparison of epicardial fat thickness (EFT) values between diabetes mellitus and control groups (a) and high/low Klotho subgroups (b). Scatter plot graph summarizing the negative correlation between serum Klotho levels and EFT values (c). Journal of Diabetes and Its Complications 2016 30, 126-132DOI: (10.1016/j.jdiacomp.2015.09.013) Copyright © 2016 Elsevier Inc. Terms and Conditions

Fig. 2 Comparison of flow mediated dilatation (FMD) percentage values between diabetes mellitus and control groups (a) and high/low Klotho subgroups (b). Scatter plot graph summarizing the positive correlation between serum Klotho levels and FMD values (c). Journal of Diabetes and Its Complications 2016 30, 126-132DOI: (10.1016/j.jdiacomp.2015.09.013) Copyright © 2016 Elsevier Inc. Terms and Conditions

Fig. 3 Comparison of carotis intima–media thickness (CIMT) values between diabetes mellitus and control groups (a) and high/low Klotho subgroups (b). Scatter plot graph summarizing the negative correlation between serum Klotho levels and CIMT values (c). Journal of Diabetes and Its Complications 2016 30, 126-132DOI: (10.1016/j.jdiacomp.2015.09.013) Copyright © 2016 Elsevier Inc. Terms and Conditions

Fig. 4 Comparison of left ventricle longitudinal global strain (LVLGS) values between diabetes mellitus and control groups (a) and high/low Klotho subgroups (b). Scatter plot graph summarizing the positive correlation between serum Klotho levels and LVLGS values (c). Journal of Diabetes and Its Complications 2016 30, 126-132DOI: (10.1016/j.jdiacomp.2015.09.013) Copyright © 2016 Elsevier Inc. Terms and Conditions