Nicole C. Hank, MHSM Neurovitality Arizona, United States of America Neuro-V: An all in One Natural Supplement to Improve Nerve Regeneration, Increase Cognitive and Physical Performance and Effects on Neuroprotection Nicole C. Hank, MHSM Neurovitality Arizona, United States of America

summary Antioxidants and Nutritional Supplements are not required by FDA for approval Neuropathy is a nerve disorder that does not have a cure Many pharmacological therapies are not efficacious Do not regevenate nerves Academy of Neurology required more forms of therapy

Summary Antioxidants and vitamins have a myriad of benefits including disease prevention and management B-Vitamins, Alpha Lipoic Acid, Acetyl-L- Cartinine has many functions and have demonstrated nerve regeneration Neuro-V, a nutritional combined supplement can alleviate pain and symptoms from neuropathy

Problems Many pharmacologic therapies have undesired side effects Do not regenevnate nerves Do not have the ability to provide neuroprotection

Problems Antioxidants and vitamins are not FDA approved Neuro-V has not been in clinical trials Neuro-V is not FDA approved, but is globally available

Methods Twenty Four patients with peripheral and small fiber neuropathy were given 1 month supply of Neuro-V as adjunctive therapy Brief Pain Inventory (short form) administered at baseline and at Month 1 Visual Analog Scale was administered at baseline and at Month 1

Results Sixty-five percent of patients responded positively Side effects only seen in 7% of study population 92% of patients remained on Neuro-V after study abated

Results Over 400 patients have taken Neuro-V for neuropathy Components of Neuro-V also have the capability of improving cognitive impairment and are neuroprotective Athletes and elderly use Neuro-V prophalically Further studies need to be conducted for effacacy

References Bril V, England J, Franklin GM, et al (2011) American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine. Evidence-based guideline. Treatment of painful diabetic neuropathy, Neurology, 77 (6): 603. Chiechio S, Copani A, Nicoletti F, Gereau R (2006). Acety-l-carnitine: a proposed therapeutic agent for painful peripheral neuropathies. Curr Neuropharmacol 4(3):233-237. Holmay, M. J., M. Terpstra, L. D. Coles, U. Mishra, M. Ahlskog, G. Oz, et al. (2013) N- acetylcysteine boosts brain and blood glutathione in gaucher and Parkinson diseases. Clin. Neuropharmacol 36:103–106. Javed, S., Petropoulos, I., Alam, U., and Malik, A (2015) Treatment of painful diabetic neuropathy Ther Adv Chronic Dis. Jan; 6(1): 15–28. Kaczor, K. (2010)The Therapeutic Effects of Acetyl-L-Carnitine on Peripheral Neuropathy: A Review of the LiteraturePeripheral neuropathy is nerve conduction disruption that occurs outside of the central nervous system. Natural Medicine Journal. Vol. 2 Issue 8.

Conclusions Neuro-V has been demonstrated to be Safe Effective Neuro-V will continue to be sold globally Neuro-V will expand marketing to athletes and elderly besides neuropathy