PI 3-kinase inhibition has no effect on ANG II induced extracellular recognition kinase (ERK) 1/2 activation. PI 3-kinase inhibition has no effect on ANG.

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Date of download: 6/22/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Reduction of Hyaluronan-CD44–Mediated Growth, Migration,
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PI 3-kinase inhibition has no effect on ANG II induced extracellular recognition kinase (ERK) 1/2 activation. PI 3-kinase inhibition has no effect on ANG II induced extracellular recognition kinase (ERK) 1/2 activation. VSMC were pretreated with 1–20 μM LY-294002 for 45 min before treatment with ANG II for 5 min. Immunoblot analysis was performed with anti-phospho-specific ERK1/2 antibodies (1:5,000). Petra Rocic et al. Am J Physiol Cell Physiol 2001;280:C90-C99 ©2001 by American Physiological Society