Date of download: 10/17/2017 Copyright © ASME. All rights reserved. From: A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues J. Med. Devices. 2011;5(4):041006-041006-11. doi:10.1115/1.4005319 Figure Legend: Diagram of a bioreactor for mechanobiological research and tissue engineering

Date of download: 10/17/2017 Copyright © ASME. All rights reserved. From: A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues J. Med. Devices. 2011;5(4):041006-041006-11. doi:10.1115/1.4005319 Figure Legend: Roadmap phase 1: step-by-step definition and analysis of the bioreactor cycle

Date of download: 10/17/2017 Copyright © ASME. All rights reserved. From: A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues J. Med. Devices. 2011;5(4):041006-041006-11. doi:10.1115/1.4005319 Figure Legend: Roadmap phase 2: definition and analysis of stimulation and characterization per operation

Date of download: 10/17/2017 Copyright © ASME. All rights reserved. From: A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues J. Med. Devices. 2011;5(4):041006-041006-11. doi:10.1115/1.4005319 Figure Legend: Use cycle of a bioreactor designed for experiments on rat tail tendons

Date of download: 10/17/2017 Copyright © ASME. All rights reserved. From: A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues J. Med. Devices. 2011;5(4):041006-041006-11. doi:10.1115/1.4005319 Figure Legend: Behavior of viscoelastic materials under strain and stress controlled cyclic loading

Date of download: 10/17/2017 Copyright © ASME. All rights reserved. From: A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues J. Med. Devices. 2011;5(4):041006-041006-11. doi:10.1115/1.4005319 Figure Legend: Impact of rest periods on the behavior of viscoelastic materials under strain controlled cyclic loading

Date of download: 10/17/2017 Copyright © ASME. All rights reserved. From: A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues J. Med. Devices. 2011;5(4):041006-041006-11. doi:10.1115/1.4005319 Figure Legend: Preloading operation (creep test at 3 g for 5 min) done on a rat tail tendon with an oversized (3 kg) load cell. The noise is relatively important in comparison with the signal.

Date of download: 10/17/2017 Copyright © ASME. All rights reserved. From: A Roadmap for the Design of Bioreactors in Mechanobiological Research and Engineering of Load-Bearing Tissues J. Med. Devices. 2011;5(4):041006-041006-11. doi:10.1115/1.4005319 Figure Legend: First half of a sine wave (160 μm peak-to-peak amplitude, 1 Hz frequency) modeled with increasing resolutions from 0.5 to 5 μm