An Integrated Analysis of Liver Safety Data from Orlistat Clinical Trials Obes Facts 2012;5:485–494 - DOI:10.1159/000341589 Fig. 1. Occurrence of two.

Slides:

Advertisements

Similar presentations

Doxycycline in Eradication Therapy of Helicobacter pylori - A Systematic Review and Meta-Analysis Digestion 2016;93: DOI: /

Advertisements

The Effects of Growth Hormone and Sex Steroid on Lean Body Mass, Fat Mass, Muscle Strength, Cardiovascular Endurance and Adverse Events in Healthy Elderly.

Successful Treatment for Chronic Hepatitis C-Autoimmune Hepatitis Overlap Syndrome due to Daclatasvir and Asunaprevir Case Rep Gastroenterol 2017;11:305–311.

Treatment of Primary and Metastatic Multifocal Mucosal Melanoma of the Oral Cavity with Imatinib - DOI: / Fig. 1. Multiple, partially confluent,

Findings of Vascular Brain Injury and Structural Loss from Cranial Magnetic Resonance Imaging in Elderly American Indians: The Strong Heart Study Neuroepidemiology.

Aesthet Dermatol Surg 2017;1:2–7 - DOI: /

Functional Roles of Prolines at Amelogenin C Terminal during Tooth Enamel Formation Cells Tissues Organs 2009;189:203–206 - DOI: / © 2008.

Cardiovascular Disease Mortality and Cancer Incidence in Vegetarians: A Meta-Analysis and Systematic Review Ann Nutr Metab 2012;60:233–240 - DOI: /

The Mechanism of Procedural Stroke Following Carotid Endarterectomy within the Asymptomatic Carotid Surgery Trial 1 Cerebrovasc Dis 2016;42:

Triple Negative Breast Cancer versus Non-Triple Negative Breast Cancer Treated with Breast Conservation Surgery Followed by Radiotherapy: A Systematic.

Puberty and Ovarian Function in Girls with Type 1 Diabetes Mellitus

Positive Expiratory Pressure via Mask Does Not Improve Ventilation Inhomogeneity More than Huffing and Coughing in Individuals with Stable Chronic Obstructive.

Paroxetine, Cognitive Therapy or Their Combination in the Treatment of Social Anxiety Disorder with and without Avoidant Personality Disorder: A Randomized.

Early Administration of Low-Dose Aspirin for the Prevention of Preterm and Term Preeclampsia: A Systematic Review and Meta-Analysis Fetal Diagn Ther 2012;31:141–146.

Familial Aggregation of Cranial Tremor in Familial Essential Tremor

Neuroepidemiology 2015;44: DOI: /

Systematic Review of Zinc Fortification Trials

Deferasirox Decreases Liver Iron Concentration in Iron-Overloaded Patients with Myelodysplastic Syndromes, Aplastic Anemia and Other Rare Anemias Acta.

Type 1 Diabetes Duration Decreases Pulmonary Diffusing Capacity during Exercise Respiration 2016;91: DOI: / Fig. 1. DLCO/BSA at.

Qualitative and Quantitative Issues of Lymph Nodes as Prognostic Factor in Colon Cancer Dig Surg 2013;30: DOI: / Fig. 1. Multiple.

Follicular Cell-Derived Thyroid Cancer in Children

Renalase, a Novel Enzyme Involved in Blood Pressure Regulation, Is Related to Kidney Function but Not to Blood Pressure in Hemodialysis Patients Kidney.

Atorvastatin Reduces Plaque Vulnerability in an Atherosclerotic Rabbit Model by Altering the 5-Lipoxygenase Pathway Cardiology 2010;115:221–228 - DOI: /

Management of Subclinical Hypothyroidism: The Thyroidologists’ View

Factors Associated with Blood Pressure Variability Based on Ambulatory Blood Pressure Monitoring in Subjects with Hypertension in China Kidney Blood Press.

Effect of a Non-Calcium-Based Phosphate Binder on Fibroblast Growth Factor 23 in Chronic Kidney Disease Nephron Clin Pract 2013;123: DOI: /

Biochemical Predictors of Outcome of Pituitary Surgery for Cushing’s Disease Neuroendocrinology 2010;91:169–178 - DOI: / © 2009 S. Karger.

Can the American Thyroid Association Risk of Recurrence Predict Radioiodine Refractory Disease in Differentiated Thyroid Cancer Eur Thyroid J 2016;5:

Am J Nephrol 2013;38: DOI: / Fig. 1. Study selection process.

Cell Physiol Biochem 2015;37: DOI: /

The Effect of Vaginal Oestriol Cream on Subjective and Objective Symptoms of Stress Urinary Incontinence and Vaginal Atrophy: An International Multi-Centre.

A Review of the Use of Biotin for Hair Loss

Quantitative Renal Echogenicity as a Tool for Diagnosis of Advanced Chronic Kidney Disease in Patients with Glomerulopathies and no Liver Disease Kidney.

Renal Parenchymal Hypoxia, Hypoxia Response and the Progression of Chronic Kidney Disease Am J Nephrol 2008;28:998– DOI: / © 2008.

Effectiveness and Cost-Effectiveness of Dialectical Behaviour Therapy for Self-Harming Patients with Personality Disorder: A Pragmatic Randomised Controlled.

Tumors Presenting as Multiple Cranial Nerve Palsies

Local Breast Cancer Recurrence after Mastectomy and Breast-Conserving Surgery for Paget's Disease: A Meta-Analysis Breast Care 2014;9: DOI: /

Comparison of the Effects of Pioglitazone versus Placebo when Given in Addition to Standard Insulin Treatment in Patients with Type 2 Diabetes Mellitus.

Creatinine-Based Glomerular Filtration Rates and Microalbuminuria for Detecting Metabolic Abnormalities in US Adults: The National Health and Nutrition.

Shock due to Splenic Injury after Colonoscopy

Diverticular Bleeding of the Colon during Combination Chemotherapy with Bevacizumab and Paclitaxel for Recurrent Breast Cancer Case Rep Oncol 2013;6:50–54.

Anti-Infective Locks for Treatment of Central Line-Associated Bloodstream Infection: A Systematic Review and Meta-Analysis Am J Nephrol 2011;34:415–422.

Potential Contributions of Heat Shock Proteins to Temperature-Dependent Sex Determination in the American Alligator Sex Dev 2010;4:73–87 - DOI: /

Management of Spontaneous Hepatic Rupture on Top of HELLP Syndrome: Case Report and Review of the Literature Viszeralmedizin 2015;31: DOI: /

Treatment of Multiple Actinic Keratosis and Field of Cancerization with Topical Piroxicam 0.8% and Sunscreen 50+ in Organ Transplant Recipients: A Series.

Pancreatic Acinar Cell Carcinoma

Prophylactic Antibiotics Reduce Pancreatic Necrosis in Acute Necrotizing Pancreatitis: A Meta-Analysis of Randomized Trials Dig Surg 2010;27:442–449 -

Imaging Modalities for Focal Nodular Hyperplasia and Hepatocellular Adenoma Dig Surg 2010;27:46–55 - DOI: / © 2010 S. Karger AG, Basel.

Diagnostic Value of the CD103+CD4+/CD4+ Ratio to Differentiate Sarcoidosis from Other Causes of Lymphocytic Alveolitis Respiration 2016;91: DOI: /

The Impact of Case Finding on the Recruitment Yield for COPD Research in Primary Care: An Observational Study Respiration 2016;92: DOI: /

Efficacy of Combined Levonorgestrel-Releasing Intrauterine System with Gonadotropin-Releasing Hormone Analog for the Treatment of Adenomyosis Med Princ.

Evaluating Quality in Clinical Cancer Research: The M. D

Pulmonary Hypertension Is Associated with Mortality and Cardiovascular Events in Chronic Kidney Disease Patients Am J Nephrol 2017;45: DOI: /

Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study Am J Nephrol 2016;43:

TPOAb and Thyroid Function Are Not Associated with Breast Cancer Outcome: Evidence from a Large-Scale Study Using Data from the Taxotere as Adjuvant Chemotherapy.

The Broken Health Information Technology Innovation Pipeline: A Perspective from the NODE Health Consortium - DOI: / Fig. 1. The Food and.

Electrochemotherapy in the Treatment of Massive, Multisite Breast Cancer Metastasis to the Skin and Subcutaneous Tissue: A Case Report Breast Care 2016;11:

The Effect of Upper Airway Surgery on Continuous Positive Airway Pressure Levels and Adherence: A Systematic Review and Meta-Analysis ORL 2016;78:

Cord Blood IL-16 Is Associated with 3-Year Neurodevelopmental Outcomes in Perinatal Asphyxia and Hypoxic-Ischaemic Encephalopathy Dev Neurosci 2017;39:59-65.

Cell Physiol Biochem 2016;38: DOI: /

A Case Report Demonstrating the Potential Clinical Benefit of Exhaustive Molecular Profiling in an Aggressive Muscle-Invasive High-Grade Metastatic Urothelial.

Successful Treatment with S-1 and Oxaliplatin Combination Therapy in an Elderly Patient with Metastatic Colorectal Cancer Initially Presenting with Membranous.

Intra-Arterial Mechanical Thrombectomy: An Effective Treatment for Ischemic Stroke Caused by Endocarditis Case Rep Neurol 2016;8:229–233 - DOI: /

Chronic Hepatitis B Infection is Associated with Decreased Risk of Preeclampsia: A Meta-Analysis of Observational Studies Cell Physiol Biochem 2016;38:

Placebo-Controlled, Double-Blind, Prospective, Randomized Study on the Effect of Octreotide LAR in the Control of Tumor Growth in Patients with Metastatic.

Adjuvant Dose-Dense Chemotherapy in Breast Cancer: Standard of Care in High-Risk Patients Breast Care 2016;11: DOI: / Fig. 1. Strategies.

Intrathoracic Hernia after Total Gastrectomy

Spot Check Analysis of Gas Exchange: Invasive versus Noninvasive Methods Respiration 2015;89: DOI: / Fig. 1. Study protocol. CBGl.

A Pathological Scoring System to Predict Renal Outcome in Diabetic Nephropathy Am J Nephrol 2015;41: DOI: / Fig. 1. Renal survival.

Digital Medicine: A Primer on Measurement

Presentation transcript:

An Integrated Analysis of Liver Safety Data from Orlistat Clinical Trials Obes Facts 2012;5:485–494 - DOI:10.1159/000341589 Fig. 1. Occurrence of two successive abnormal ALT measurements (60 and 120 mg orlistat combined). © 2012 S. Karger AG, Basel

An Integrated Analysis of Liver Safety Data from Orlistat Clinical Trials Obes Facts 2012;5:485–494 - DOI:10.1159/000341589 Fig. 2. Occurrence of two successive abnormal bilirubin measurements (60 and 120 mg orlistat combined). © 2012 S. Karger AG, Basel

An Integrated Analysis of Liver Safety Data from Orlistat Clinical Trials Obes Facts 2012;5:485–494 - DOI:10.1159/000341589 Fig. 3. mDISH plot between orlistat (60 and 120 mg combined) and placebo. © 2012 S. Karger AG, Basel

An Integrated Analysis of Liver Safety Data from Orlistat Clinical Trials Obes Facts 2012;5:485–494 - DOI:10.1159/000341589 Fig. 4. A subject showing high ALT and bilirubin. © 2012 S. Karger AG, Basel

An Integrated Analysis of Liver Safety Data from Orlistat Clinical Trials Obes Facts 2012;5:485–494 - DOI:10.1159/000341589 Fig. 5. K-M estimates of difference in treatment-emergent LFT signals between orlistat (60 and 120 mg combined) and placebo. Note: Vertical line represents error bar (± standard error). © 2012 S. Karger AG, Basel