Volume 55, Issue 2, Pages (February 1999)

Slides:

Advertisements

Similar presentations

Renal Stress Testing in the Assessment of Kidney Disease Lakhmir S. Chawla, Claudio Ronco Kidney International Reports Volume 1, Issue 1, Pages (May.

Advertisements

M. Mizobuchi, J.L. Finch, D.R. Martin, E. Slatopolsky

Volume 59, Issue 4, Pages (April 2001)

A potential role of chondroitin sulfate on bone in osteoarthritis: inhibition of prostaglandin E2 and matrix metalloproteinases synthesis in interleukin-1β-

Volume 62, Issue 6, Pages (December 2002)

Anemia management in chronic kidney disease

IL-2–mediated apoptosis of kidney tubular epithelial cells is regulated by the caspase-8 inhibitor c-FLIP Caigan Du, Qiunong Guan, Ziqin Yin, Robert.

Volume 71, Issue 6, Pages (March 2007)

Shining light on vitamin D trials in chronic kidney disease

Prehypertension and chronic kidney disease: the ox or the plow?

Reassessment of the care of the patient with chronic kidney disease

Dysregulation of LDL receptor under the influence of inflammatory cytokines: A new pathway for foam cell formation1 Dr Xiong Z. Ruan, Zac Varghese, Stephen.

Volume 54, Issue 1, Pages (July 1998)

John P. Middleton, Patrick H. Pun Kidney International

TGF-β isoforms in renal fibrogenesis

M. Fukagawa, S. Nakanishi, J.J. Kazama Kidney International

Shiga toxin 1 elicits diverse biologic responses in mesangial cells

Ultraviolet Light and Interleukin-10 Modulate Expression of Cytokines by Transformed Human Dermal Microvascular Endothelial Cells (HMEC-1) Thomas Scholzen,

Volume 72, Issue 6, Pages (September 2007)

Comorbidity and confounding in end-stage renal disease

Volume 74, Issue 3, Pages (August 2008)

Volume 70, Issue 11, Pages (December 2006)

Volume 78, Pages S33-S36 (August 2010)

Interleukin-1β regulation of gonadotropin-releasing hormone messenger ribonucleic acid in cultured human endometrial stromal cells Hong-Yuan Huang, M.D.,

The epidemiology of chronic kidney disease

Use of vitamin D in chronic kidney disease patients

Volume 87, Issue 2, Pages (February 2015)

Paricalcitol therapy for secondary hyperparathyroidism in patients on maintenance hemodialysis previously treated with calcitriol: A single-center crossover.

Volume 70, Issue 12, Pages (December 2006)

Volume 54, Issue 6, Pages (January 1998)

Nephrology Crossword: History of nephrology

Fructose intake as a risk factor for kidney stone disease

Role of vitamin D receptor activators on cardiovascular risk

The third World Kidney Day: Looking back and thinking forward

Volume 17, Issue 2, Pages (February 1950)

M. Mizobuchi, J.L. Finch, D.R. Martin, E. Slatopolsky

Effects of hemodialysis on cardiac function

Extracorporeal therapy in sepsis: are we there yet?

Volume 69, Issue 12, Pages (June 2006)

Volume 69, Issue 3, Pages (February 2006)

Volume 87, Issue 3, Pages (March 2015)

Volume 59, Issue 2, Pages (February 2001)

Methods for guideline development

Eva Balint, Cory F. Marshall, Dr Stuart M. Sprague

Volume 56, Pages S137-S140 (July 1999)

The global challenge of chronic kidney disease

Nephrology Crossword: Glomerulonephritis

Tohru Umekawa, Nasser Chegini, Saeed R. Khan, Ph.D.

Marta Soler, Mercedes Camacho, Ricard Solá, Luís Vila

Volume 71, Issue 4, Pages (February 2007)

A man with a hole in his penis

Organ transplantation goes to the movies

Volume 63, Issue 2, Pages (February 2003)

Volume 55, Pages S3-S16 (June 1999)

Volume 80, Issue 10, Pages (November 2011)

Is it the low-protein diet or simply the salt restriction?

Is complement a target for therapy in renal disease?

David A. Ferenbach, David C. Kluth, Jeremy Hughes Kidney International

Volume 70, Issue 3, Pages (August 2006)

Advisory about gadolinium calls for caution in the treatment of uremic patients with lanthanum carbonate S. Aime, C. Canavese, P. Stratta Kidney International

Recent developments in the management of secondary hyperparathyroidism

Volume 70, Issue 5, Pages (September 2006)

Tobias Breidthardt, Alexandre Mebazaa, Christian E. Mueller

Volume 62, Issue 5, (November 2002)

IL-1β induces VEGF, independently of PGE2 induction, mainly through the PI3-K/mTOR pathway in renal mesangial cells D. Solà-Villà, M. Camacho, R. Solà,

Hisataka Kobayashi, Peter L. Choyke Kidney International

Volume 61, Issue 2, Pages (February 2002)

Oxalate stimulates IL-6 production in HK-2 cells, a line of human renal proximal tubular epithelial cells M.E.I. Y.I. Huang, Lakshmi S. Chaturvedi, Sweaty.

Volume 57, Issue 2, Pages (October 2000)

Volume 55, Issue 4, Pages (April 1999)

Presentation transcript:

Volume 55, Issue 2, Pages 500-511 (February 1999) Effects of new analogues of vitamin D on bone cells: Implications for treatment of uremic bone disease Christopher W. Mcintyre, Neil J. Schroeder, Jacqueline M. Burrin, John Cunningham Kidney International Volume 55, Issue 2, Pages 500-511 (February 1999) DOI: 10.1046/j.1523-1755.1999.00289.x Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 1 Molecular structures of calcitriol, paricalcitol, 22-oxacalcitriol (OCT), and 1,25 (OH)2DHT2. Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 2 Release of interleukin (IL)-6 from MG 63 cells after incubation with the sterols for six hours. *P < 0.05 significance compared with CS-medium control values. N = 36 for each sterol. Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 3 Release of IL-6 from MG 63 cells after incubation with the sterols for 24hours. *P < 0.05 significance compared with CS-medium control values. N = 64 for each sterol. Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 4 Release of IL-6 from SaOS-2 cells after incubation with the sterols for 24hours. P < 0.05 significance compared with CS-medium control values. N = 32 for each sterol. Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 5 Dose response curve for IL-6 release from MG 63 cells in response to 24-hour incubation with exogenous IL-1β. Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 6 Effect of the amount of cDNA used per PCR reaction on the optical density of the final product. Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 7 Effect of the vitamin D sterols on IL-6 mRNA levels in MG 63 cells after six hours. *Indicates statistically significant difference between sterol-treated mRNA level and control mRNA level (P < 0.05, N = 3). Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 8 Effect of the vitamin D sterols on IL-6 mRNA levels in MG 63 cells after 24hours. *Indicates statistically significant difference between sterol-treated mRNA level and control mRNA level (P < 0.05, N = 3). Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 9 Effect of the vitamin D sterols on IL-6 mRNA levels in SaOS-2 cells after 24hours. *Indicates statistically significant difference between sterol-treated mRNA level and control mRNA level (P < 0.05, N = 3). Kidney International 1999 55, 500-511DOI: (10.1046/j.1523-1755.1999.00289.x) Copyright © 1999 International Society of Nephrology Terms and Conditions