A. Timeline of select milestones in HIV management

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Presentation transcript:

A. Timeline of select milestones in HIV management A. Timeline of select milestones in HIV management. Genomic advances are shown in bold type. The approvals and recommendations indicated apply to the United States. ARV, antiretroviral; AZT, zidovudine; NRTI, nucleoside reverse transcriptase (RT) inhibitor; NNRTI, non-nucleoside RT inhibitor; PI, protease inhibitor. B. Viral dynamics in the natural history of HIV infection. Three diagnostic markers are shown: HIV antibody (Ab), p24 antigen (p24), and viral load (VL). Dashed gray line represents limit of detection. (Adapted from data in HH Fiebig et al: Dynamics of HIV viremia and antibody seroconversion in plasma donors: Implications for diagnosis and staging of primary HIV infection. AIDS 17:1871, 2003.) Source: Genomics and Infectious Disease, Harrison's Principles of Internal Medicine, 19e Citation: Kasper D, Fauci A, Hauser S, Longo D, Jameson J, Loscalzo J. Harrison's Principles of Internal Medicine, 19e; 2015 Available at: http://accesspharmacy.mhmedical.com/DownloadImage.aspx?image=/data/Books/1130/kas_ch146_f002.png&sec=98712517&BookID=1130&ChapterSecID=63652289&imagename= Accessed: October 18, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved