The Longitudinal Study of Liver Cysts in Patients With Autosomal Dominant Polycystic Kidney Disease and Polycystic Liver Disease Ryo Matsuura, Kenjiro.

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The Longitudinal Study of Liver Cysts in Patients With Autosomal Dominant Polycystic Kidney Disease and Polycystic Liver Disease Ryo Matsuura, Kenjiro Honda, Yoshifumi Hamasaki, Kent Doi, Eisei Noiri, Masaomi Nangaku Kidney International Reports Volume 2, Issue 1, Pages 60-65 (January 2017) DOI: 10.1016/j.ekir.2016.09.061 Copyright © 2016 International Society of Nephrology Terms and Conditions

Figure 1 TLV change in patients with ADPKD. The vertical axis represents the change of TLV compared with baseline (%), whereas the horizontal axis represents time (days). ADPKD, autosomal dominant polycystic kidney disease; PCLD, polycystic liver disease; TLV, total liver volume. Kidney International Reports 2017 2, 60-65DOI: (10.1016/j.ekir.2016.09.061) Copyright © 2016 International Society of Nephrology Terms and Conditions

Figure 2 Association between liver cyst volume and the diameter of cyst in PCLD patients with ADPKD. ADPKD, autosomal dominant polycystic kidney disease; PCLD, polycystic liver disease. Kidney International Reports 2017 2, 60-65DOI: (10.1016/j.ekir.2016.09.061) Copyright © 2016 International Society of Nephrology Terms and Conditions

Figure 3 (a) Clinical course of cyst growth in PCLD patients with ADPKD and patients without ADPKD. The vertical axis is the ratio of cyst volume to baseline (day 0) volume. (b) Cyst growth rate in PCLD patients with ADPKD and patients without ADPKD. *P < 0.001. ADPKD, autosomal dominant polycystic kidney disease; PCLD, polycystic liver disease. Kidney International Reports 2017 2, 60-65DOI: (10.1016/j.ekir.2016.09.061) Copyright © 2016 International Society of Nephrology Terms and Conditions

Figure 4 The proportion of (a) parenchyma and (b) cyst at baseline and time proceeding in PCLD patients with ADPKD. *P = 0.001. ADPKD, autosomal dominant polycystic kidney disease; PCLD, polycystic liver disease. Kidney International Reports 2017 2, 60-65DOI: (10.1016/j.ekir.2016.09.061) Copyright © 2016 International Society of Nephrology Terms and Conditions

Figure 5 The relationship between TLV and cyst volume. (a) When cyst volume is mild to moderate, parenchymal volume decreases and TLV does not change, whereas the cyst grows. (b) When cyst volume is severely developed, cyst volume and TLV correlate. TLV, total liver volume. Kidney International Reports 2017 2, 60-65DOI: (10.1016/j.ekir.2016.09.061) Copyright © 2016 International Society of Nephrology Terms and Conditions