Fig. 1. Kaplan-Meir survival curves for Stoke Cushing's patients, with follow-up duration in years on the x-axis. Number of patients in each subgroup is.

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Fig. 1. Kaplan-Meir survival curves for Stoke Cushing's patients, with follow-up duration in years on the x-axis. Number of patients in each subgroup is shown in parentheses. Upper left, Remission vs. persistent disease; upper right, diabetes vs. no diabetes; P value compares the two groups. Bottom, Hypertension vs. no hypertension. From: Mortality and Morbidity in Cushing's Disease over 50 Years in Stoke-on-Trent, UK: Audit and Meta-Analysis of Literature J Clin Endocrinol Metab. 2011;96(3):632-642. doi:10.1210/jc.2010-1942 J Clin Endocrinol Metab | Copyright © 2011 by The Endocrine Society

Fig. 2. Forest plot of overall SMRs from seven studies (patients in remission and with persistent disease combined). Solid black line, Unity (i.e. no difference in SMR from that expected from normal population); dotted line, mean pooled SMR through center of diamond (the horizontal points of which show the 95% CIs). ES, Estimated SMR with 95% CIs. From: Mortality and Morbidity in Cushing's Disease over 50 Years in Stoke-on-Trent, UK: Audit and Meta-Analysis of Literature J Clin Endocrinol Metab. 2011;96(3):632-642. doi:10.1210/jc.2010-1942 J Clin Endocrinol Metab | Copyright © 2011 by The Endocrine Society

Fig. 3. Forest plot of SMRs from four studies for patients in remission (A) and for patients with persistent disease (B). See Fig. 2 legend for detailed description. From: Mortality and Morbidity in Cushing's Disease over 50 Years in Stoke-on-Trent, UK: Audit and Meta-Analysis of Literature J Clin Endocrinol Metab. 2011;96(3):632-642. doi:10.1210/jc.2010-1942 J Clin Endocrinol Metab | Copyright © 2011 by The Endocrine Society