Pathogenesis of bone diseases in chronic kidney disease

Slides:

Advertisements

Similar presentations

Patterns of chronic H pylori infection with respect to acid production and pathology. Left: Acid hyposecretion. H pylori infection of the stomach body.

Advertisements

Inverse sigmoidal relationship between parathyroid hormone (PTH) release and the extracellular calcium concentration in human studies (upper panel) and.

Paralysis of conjugate gaze to the opposite side: Frontal contraversive eye field or projecting fibers Source: Cerebrovascular Diseases, Harrison's Principles.

Schematic drawing of a Nissl-stained motor neuron

Life cycle of microsporidia

Brief pain inventory. (Reproduced with permission from the University of Texas MD Anderson Cancer Center, Department of Symptom Research, Houston, TX.

(A) Serum antibody and antigen levels in hepatitis A and hepatitis B

Paralysis or weakness of all extremities, plus all bulbar musculature: Corticobulbar and corticospinal tracts bilaterally Source: Cerebrovascular Diseases,

Transection of the utero-ovarian ligament

An above-knee artificial leg invented by Ambroise Paré (mid-16th century). (From Paré A: Oeuvres Complétes, Paris, 1840, with permission from the National.

Mechanisms of production of atheroma

The importance of surface tension

Pathophysiology of esophageal reflux disease

In certain patients with the long QT syndrome, potassium channel function is reduced (diagonal arrows), which leads to prolongation of the action potential.

Stages in the development of type 2 DM from a pre-diabetic, insulin-resistant state. As insulin sensitivity decreases, insulin-mediated glucose disposal.

Complement reaction sequence and infections associated with deficiency states. (Redrawn, with permission, from Nairn R. Immunology. In: Brooks GF et al,

(Reproduced, with permission, from Findling JW, et al

A chamber designed to treat multiple patients

Patterns of chronic H pylori infection with respect to acid production and pathology. Left: Acid hyposecretion. H pylori infection of the stomach body.

Treatment approaches for Crohn disease. (Adapted from Hemstreet BA

Deming's System of Profound Knowledge

Kidney Disease Improving Global Outcome (KDIGO) classification of chronic kidney disease (CKD). Gradation of color from green to red corresponds to increasing.

Nine patterns of inflammatory skin disease. (See also Table 8–1.)

Forearm support for sustained work at the computer.

Diagnostic algorithm for normocytic anemia.

Relation of H pylori infection to upper GI tract conditions

Algorithm for the management of aortic valve stenosis

Hypothetical distribution of test results for healthy and diseased individuals. The position of the "cutoff point" between "normal" and "abnormal" (or.

Diagram of events in the cardiac cycle

Radiographs of the right femur in a patient with juvenile Paget disease before (left) and after (right) 10 months of treatment with calcitonin. Note the.

Ochronotic pigmentation of the femur of a 56-year-old alkaptonuric patient. (Courtesy of Dr. H. W. Edmonds of the Washington Hospital Center, Washington,

Mechanisms leading to Down syndrome

Internal hemorrhoids. (Used, with permission, from John Cello, MD.)

Pathophysiology of ischemia-induced acute kidney failure

Subdivision of conducting airways and terminal respiratory units

Various symptoms of pituitary tumor

In diastolic dysfunction, the diastolic pressure-volume relationship is shifted upward and to the left (dashed line), which leads to an elevated left ventricular.

Hydronephrosis. A: Longitudinal scan from a patient with hydronephrosis due to chronic reflux. Numerous dilated fluid-filled spaces (calices) are seen.

Stages in the accumulation of pulmonary edema fluid

Rearfoot movement during running

D-dimer and helical CT-PA based diagnostic algorithm for PE

Hypothalamic, pituitary, and adrenal cortical relationships

Hairy cell leukemia. (Bone marrow core biopsy, 50 ×

Biosynthesis and metabolism of testosterone

Diagram of events in the cardiac cycle

Pathophysiological alterations leading to neuronal injury during bacterial meningitis. BBB, blood-brain barrier; CBV, cerebral blood volume. (Redrawn,

Proposed pathogenesis of Graves disease

Hypothalamic, pituitary, and adrenal cortical relationships

Pathogenesis of CKD-MBD and renal osteodystrophy

Prostate cancer mortality as a factor of Gleason score and age at diagnosis in men managed conservatively. (Adapted, with permission, from Albertsen PC.

Note: A multivariate analysis suggests that a model that adds clinical and demographic information may perform better than the nomogram alone. (See O'Neill.

(Adapted and reprinted with permission, from Hughes JM et al: Effect of lung volume on the distribution of pulmonary blood flow in man. Respir Physiol.

Relationship of Down syndrome to maternal age

Estimated number of AIDS cases and AIDS deaths, United States, 1985–2011. (From CDC.) Source: Human Immunodeficiency Virus Disease: AIDS and Related Disorders,

Adapted with permission from Hsia, J et al

Internal hemorrhoids. (Used, with permission, from John Cello, MD.)

Aortic insufficiency (regurgitation)

Model for the histological and genetic progression from normal cells (far left) through pancreatic intraepithelial neoplasia (PanIN) lesions (center),

Mean rates of insulin and glucagon delivery from an artificial pancreas at various blood glucose levels. The device was programmed to establish and maintain.

(Copyright © 1977 American Diabetes Association. Marliss EB et al

Down syndrome (DS) critical region

(A) Serum antibody and antigen levels in hepatitis A and hepatitis B

Role of cobalamin (vitamin B12) and folic acid in nucleic acid and myelin metabolism. Lack of either cobalamin or folic acid retards DNA synthesis (A)

Likelihood of fragile X–associated mental retardation syndrome in an artificial pedigree. The percentages shown indicate the likelihood of clinical manifestation.

Posteroanterior chest x-ray film in a man with acute pulmonary edema resulting from left ventricular failure. Note the bat’s wing density, cardiac enlargement,

Glomerular diseases present within one of the clinical spectra shown, the exact presentation is determined by the severity of the underlying disease and.

The participation of vitamin K–dependent clotting factors highlighted in yellow in the coagulation cascade. (Modified with permission from Furie B and.

Sympathetic stimulation of the kidney leads to the release of renin, with a resultant increase in the circulating levels of angiotensin II and aldosterone.

(Redrawn, with permission, from Chandrasoma P, Taylor CR

Hypothalamic-pituitary-thyroid axis

Presentation transcript:

Pathogenesis of bone diseases in chronic kidney disease Pathogenesis of bone diseases in chronic kidney disease. (Redrawn, with permission, from Brenner BM et al. Chronic renal failure. In: Isselbacher KJ et al, eds. Harrison’s Principles of Internal Medicine, 13th ed. McGraw-Hill, 1994.) Source: Renal Disease, Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e Citation: Hammer GD, McPhee SJ. Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e; 2013 Available at: https://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/961/ham007_fig_16-06.png&sec=53632057&BookID=961&ChapterSecID=53555697&imagename= Accessed: October 19, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved