Figure 1. Forest plot: overall estimate

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Figure 1. Forest plot: overall estimate Figure 1. Forest plot: overall estimate. The denominator is the number of exposed household contacts of infectious Ebola virus disease cases. The numerator is the number of these contacts who develop disease. Abbreviations: DRC, Democratic Republic of the Congo; RE, random-effects; SAR, secondary attack rate; WHO, world health organization. From: Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection Clin Infect Dis. 2016;62(10):1277-1286. doi:10.1093/cid/ciw114 Clin Infect Dis | © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

Figure 2. Forest plot: direct contact Figure 2. Forest plot: direct contact. Abbreviations: DRC, Democratic Republic of the Congo; RE, random-effects; SAR, secondary attack rate; WHO, world health organization. From: Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection Clin Infect Dis. 2016;62(10):1277-1286. doi:10.1093/cid/ciw114 Clin Infect Dis | © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

Figure 3. Forest plot: no direct contact Figure 3. Forest plot: no direct contact. Abbreviations: DRC, Democratic Republic of the Congo; RE, random-effects; SAR, secondary attack rate. From: Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection Clin Infect Dis. 2016;62(10):1277-1286. doi:10.1093/cid/ciw114 Clin Infect Dis | © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

Figure 4. Forest plot: nursing care Figure 4. Forest plot: nursing care. For Reaves et al [18], the authors assumed that a high-risk contact was equivalent to providing nursing care as it is defined as “percutaneous or mucous membrane exposure to, or direct skin contact with blood or body fluids of an Ebola patient or a corpse … without appropriate personal protective equipment.” Abbreviations: RE, random-effects; SAR, secondary attack rate; WHO, world health organization. From: Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection Clin Infect Dis. 2016;62(10):1277-1286. doi:10.1093/cid/ciw114 Clin Infect Dis | © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

Figure 5. Forest plot: direct contact but no nursing care provided Figure 5. Forest plot: direct contact but no nursing care provided. Abbreviations: RE, random-effects; SAR, secondary attack rate. From: Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection Clin Infect Dis. 2016;62(10):1277-1286. doi:10.1093/cid/ciw114 Clin Infect Dis | © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

Figure 6. Forest plot: generation of transmission Figure 6. Forest plot: generation of transmission. Abbreviations: SAR, secondary attack rate; WHO, world health organization. From: Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection Clin Infect Dis. 2016;62(10):1277-1286. doi:10.1093/cid/ciw114 Clin Infect Dis | © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

Figure 7. Forest plot: asymptomatic proportion Figure 7. Forest plot: asymptomatic proportion. Abbreviations: DRC, Democratic Republic of the Congo; Pt. Est., point estimate; RE, random-effects. From: Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection Clin Infect Dis. 2016;62(10):1277-1286. doi:10.1093/cid/ciw114 Clin Infect Dis | © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.