Cost-effectiveness of culture-guided antimicrobial prophylaxis for the prevention of infections after prostate biopsy Chi-kong Li, Brian C.Y. Tong, Joyce.

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Presentation transcript:

Cost-effectiveness of culture-guided antimicrobial prophylaxis for the prevention of infections after prostate biopsy Chi-kong Li, Brian C.Y. Tong, Joyce H.S. You International Journal of Infectious Diseases Volume 43, Pages 7-12 (February 2016) DOI: 10.1016/j.ijid.2015.12.005 Copyright © 2015 The Authors Terms and Conditions

Figure 1 Simplified decision-analytic model (TRUSBx, transrectal ultrasound-guided prostate biopsy; FQR, fluoroquinolone resistance). International Journal of Infectious Diseases 2016 43, 7-12DOI: (10.1016/j.ijid.2015.12.005) Copyright © 2015 The Authors Terms and Conditions

Figure 2 Three-way sensitivity analysis of relative effectiveness of culture-guided versus standard prophylaxis in carriers and in non-carriers of fluoroquinolone (FQ)-resistant rectal flora on increment cost per QALY saved (ICER) at various prevalence levels of FQ-resistant rectal flora: (a) 10%, (b) 25%, (c) 40%. The threshold line divides the grey zone and white zone. Combinations of variables on the threshold line had the same cost-effectiveness for both study arms. Grey zone: combinations of variables leading to ICERs in the culture-guided group of less than the willingness-to-pay threshold (USD 39758) (preferred option=culture-guided group). White zone: combinations of variables leading to ICERs in the culture-guided group greater than the willingness-to-pay threshold (USD 39758) (preferred option=standard group). International Journal of Infectious Diseases 2016 43, 7-12DOI: (10.1016/j.ijid.2015.12.005) Copyright © 2015 The Authors Terms and Conditions

Figure 3 Scatter plot of incremental cost versus incremental QALYs saved by culture-guided prophylaxis versus standard prophylaxis. International Journal of Infectious Diseases 2016 43, 7-12DOI: (10.1016/j.ijid.2015.12.005) Copyright © 2015 The Authors Terms and Conditions