Proopiomelanocortin (POMC) processing

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Proopiomelanocortin (POMC) processing Proopiomelanocortin (POMC) processing. Corticotropin-releasing hormone stimulates the production, release, and processing of POMC, a preprohormone synthesized in the anterior pituitary. POMC is post-translationally cleaved to adrenocorticotropic hormone (ACTH); β-endorphin, an endogenous opioid peptide; and α-, β-, and γ-melanocyte-stimulating hormones (MSHs). The cellular effects of these peptides are mediated via melanocortin (ACTH and MSH) or opiate (β-endorphin) receptors. LPH, β-lipotropin. Source: Chapter 3. Anterior Pituitary Gland, Endocrine Physiology, 4e Citation: Molina PE. Endocrine Physiology, 4e; 2013 Available at: https://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/moli4/moli4_c003f005.png&sec=42540732&BookID=507&ChapterSecID=42540503&imagename= Accessed: October 19, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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